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HIV-1与趋化因子受体的研究进展

Research progress on HIV-1 and chemokine receptor
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摘要 近年来,HIV-1在借助趋化因子受体(CCR5,CXCR4)感染免疫细胞方面的研究引起了广泛关注。对趋化因子受体在HIV-1感染中结构与功能的研究对于促进人们了解艾滋病的发病机制及其预防具有重要意义。另外,对CCR5与CXCR4相关抑制剂的作用分析更为艾滋病疫苗的研制与应用提供了新的方向。本文就HIV-1与趋化因子受体的研究进展情况作一综述。 In the recent years, the research of HIV-1 infecting immunocytes by chemokine receptor CCR5 and CXCR4 was caused more attention. The research on the configuration and function of chemokine receptor during HIV-1 infection can facilitate people understanding the pathogenesis and prevention of AIDS. In addition, the analysis of function of CCR5 and CXCR4 inhibitors will provide more ways for the vaccine development and application of AIDS. The research progress of HIV-1 and chemokine receptor was introduced in the paper.
作者 马金柱 崔玉东 王北艳 朱战波 余丽芸 曹宏伟 宋佰芬
机构地区 黑龙江八一农垦大学生命科技学院
出处 《中国病原生物学杂志》 CSCD 2006年第6期465-467,共3页 Journal of Pathogen Biology
关键词 HIV-1 趋化因子受体 CCR5 CXCR4 抑制剂 综述 HIV-1 chemokine receptor CCR5 CXCR4 inhibitors review
分类号 R373.9 [医药卫生—病原生物学]
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中国病原生物学杂志
2006年 第6期

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