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过氧化物酶体增殖物激活受体γ与糖尿病肾病 被引量：1

Peroxisome proliferator-activated receptor-alpha and diabetic nephropathy
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摘要 过氧化物酶体增殖物激活受体(peroxisomeproliferator-activatedreceptor,PPAR)属于核受体超家族成员,可分为三种亚型(PPARα、PPARβ/δ、PPARγ),PPARγ在脂肪形成、脂质代谢、胰岛素敏感性、炎症反应、动脉粥样硬化、血压调节等方面发挥重要作用,本文将就其与糖尿病肾病的关系作一综述。 Peroxisome proliferator-activated receptor （PPAR）, a member of nuclear hormone receptor superfamily, has 3 subtypes, namely, PPARα, PPARβ/δ, and PPARγ; among them PPARγ plays an important role in adipogenesis, lipid metabolism, insulin sensitivity, inflammation, atherosclerosis, and blood pressure controlling. This article reviews the relationship between PPARγ and diabetic nephropathy.
作者 黄洁丽 原爱红
机构地区 同济大学附属同济医院肾脏科
出处 《第二军医大学学报》 CAS CSCD 北大核心 2006年第12期1372-1374,共3页 Academic Journal of Second Military Medical University
关键词 糖尿病肾病 PPARΓ 噻唑烷二酮类 diabetic nephropathies PPAR gamma thiazolidinediones
分类号 R587.24 [医药卫生—内分泌]
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参考文献6

二级参考文献58

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共引文献23

同被引文献27

  • 1张晓燕,陈丽红,管又飞.PPAR家族及其与代谢综合征的关系[J].生理科学进展,2005,36(1):6-12. 被引量：39
  • 2郭延军,石益海,李云,刘翠英,高秀丽,边晓霞.糖尿病肾病中过氧化物酶体增殖物激活受体作用的研究进展[J].中国实验诊断学,2005,9(3):480-480. 被引量：1
  • 3张超,管金发.过氧化物酶体增殖物激活受体γ与糖尿病肾病研究进展[J].内科理论与实践,2006,1(2):141-143. 被引量：2
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  • 7Jones JR,Barrick C,Kim KA,et al.Deletion of PPARγ in adipose tissue of mice protects against high fat diet induced obesity and insulin resistance,Proceedings of the National Academy of Sciences of the United States of America,2005,102 (17):6207-6212.
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二级引证文献2

第二军医大学学报
2006年 第12期

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