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应用基因敲除技术研究胰岛素抵抗的进展 被引量:2

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出处 《中国糖尿病杂志》 CAS CSCD 北大核心 2006年第6期474-475,共2页 Chinese Journal of Diabetes
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参考文献9

  • 1Biddinger SB,Kahn CR.From mice to men:insights into the insulin resistance syndromes.Annu Rev Physiol,2006,68:123-158.
  • 2Poy MN,Yang Y,Rezaei K,et al.CEACAM-1 regulates insulin clearance in liver.Nat Genet,2002,30:270-276.
  • 3Qiu W,Avramoglu RK,Dube N,et al.Hepatic PTP-1B expression regulates the assembly and secretion of apolipoprotein B-containing lipoproteins:evidence from protein tyrosine phosphatase-1B overexpression,knockout,and RNAi studies.Diabetes,2004,53:3057-3066.
  • 4Taniguchi CM,Kondo T,Sajan M,et al.Divergent regulation of hepatic glucose and lipid metabolism by phosphoinositide 3-kinase via Akt and PKClambda/zeta.Cell Metab,2006,3:343-353.
  • 5Rohl M,Pasparakis M,Baudler S,et al.Conditional disruption of IkappaB kinase 2 fails to prevent obesity-induced insulin resistance.J Clin Invest,2004,113:474-481.
  • 6Sotiropoulos KB,Clermont A,Yasuda Y,et al.Adipose-specific effect of rosiglitazone on vascular permeability and protein kinase C activation:novel mechanism for PPARgamma agonist's effects on edema and weight gain.FASEB J,2006,20:1203-1205.
  • 7Nehlin JO,Mogensen JP,Petterson I,et al.Selective PPAR agonists for the treatment of type 2 diabetes.Ann NY Acad Sci,2006,1067:448-453.
  • 8杨义生,陈家伦.脂肪组织分泌功能研究新进展[J].中国糖尿病杂志,2004,12(3):228-230. 被引量:14
  • 9Kadowaki T,Yamauchi T,Kubota N,et al.Adiponectin and adiponectin receptors in insulin resistance,diabetes,and the metabolic syndrome.J Clin Invest,2006,116:1784-1792.

二级参考文献23

  • 1Trayhurn P, Beattie JH. Physiological role of adipose tissue:white adipose tissue as an endocrine and secretory organ. Proc Nutr Soc, 2001,60 : 329-339.
  • 2Yang YS, Song HD, Li RY, et al. The gene expression profiling of human visceral adipose tissue and its secretory functions.Biochem Biophys Res Commun, 2003,300 : 839-846.
  • 3Zastrow O, Seidel B, Kiess W, et al. The soluble leptin receptor is crucial for leptin action: evidence from clinical and experimental data. Int J Obes Relat Metab Disord, 2003, 27: 1472-1478.
  • 4Wilsey J, Zolotukhin S, Prima V, et al. Central leptin gene therapy fails to overcome leptin resistance associated with dietinduced obesity. Am J Physiol Regul Integr Comp Physiol,2003,285 : R1011-R1020.
  • 5Shigemura N, Ohta R, Kusakabe Y, et al. Leptin modulates behavioral responses to sweet substances by influencing peripheral taste structures. Endocrinology, 2004,145 : 839-847.
  • 6Yamauchi T, Kamon J, Ito Y, et al. Cloning of adiponectin receptors that mediate antidiabetic metabolic effects. Nature,2003,423:762-769.
  • 7Diez J J, Iglesias P. The role of the novel adipocyte-derived hormone adiponectin in human disease. Eur J Endocrinol, 2003,148 : 293-300.
  • 8Kern PA, Di Gregorio GB, Lu T, et al. Adiponectin expression from human adipose tissue: relation to obesity, insulin resistance, and tumor necrosis factor-alpha expression. Diabetes,2003,52 : 1779-1785.
  • 9Kondo H, Shimomura I, Matsukawa Y, et al. Association of adiponectin mutation with type 2 diabetes: a candidate gene for the insulin resistance syndrome. Diabetes,2002,51:2325-2328.
  • 10Kaser S, Kaser A, Sandhofer A, et al. Resistin messengerRNA expression is increased by proinflammatory cytokines in vitro. Biochem Biophys Res Commun, 2003,309 : 286-290.

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