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血糖正常的代谢综合征患者血管局部氧化应激的形成及其导致动脉粥样硬化的机制 被引量：1

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作者 陆志明 余叶蓉
机构地区 四川大学华西医院内分泌科
出处 《中国糖尿病杂志》 CAS CSCD 北大核心 2006年第6期472-473,共2页 Chinese Journal of Diabetes
基金 国家自然科学基金资助项目(30370679) 教育部博士学科点科研基金资助项目(20020610087)
关键词 代谢综合征 氧化应激反应 动脉粥样硬化
分类号 R589 [医药卫生—内分泌]
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参考文献11

  • 1Russell AP,Gastaldi G,Bobbioni-Harsch E,et al.Lipid peroxidation in skeletal muscle of obese as compared to endurance-trained humans:a case of good vs.bad lipids? FEBS Lett,2003,551:104-106.
  • 2Goglia F,Skulachev VP.A function for novel uncoupling proteins:antioxidiant defense of mitochondrial matrix by translocating fatty acid peroxides from the inner to the outer membrane leaflet.FASEB J,2003,17:1585-1591.
  • 3Sorescu D,Weiss D,Lassegue B,et al.Superoxide production and expression of Nox family protein in human atherosclerosis.Circulation,2002,105:1429-1435.
  • 4Barry-Lane PA,Patterson C,van der Merwe M,et al.p47phox is required for atherosclerotic lesion progression in ApoE-/-mice.J Clin Invest,2001,108:1513-1522.
  • 5Ikeda T,Iwata K,Ochi H.Effect of insulin,proinsulin,and amylin on renin release from perfused rat kidney.Metabolism,2001,50:763-766.
  • 6Inoguchi T,Li P,Umeda F,et al.High glucose level and free fatty acid stimulate reactive oxygen species production through protein kinase C-dependent activation of NAD(P)H oxidase in cultured vascular cells.Diabetes,2000,49:1939-1945.
  • 7Hansen LL,Ikeda Y,Oken GS,et al.Insulin signaling is inhibited by micromolar concentrations of H(2)O(2).Evidence for a role of H(2)O(2) in tumor necrosis factor alpha-mediated insulin resistance.J Biol Chem,1999,274:25078-25084.
  • 8Uemura S,Matsushita H,Li W,et al.Diabetes mellitus enhances vascular matrix metalloproteinase activity:role of oxidative stress.Circ Res,2001,88:1291-1298.
  • 9Berry C,Anderson N,Kirk AJ,et al.Renin angiotensin system inhibition is associated with reduced free radical concentrations in arteries of patients with coronary.Heart,2001,86:217-220.
  • 10Takayama T,Wada A,Tsutamoto T,et al.Contribution of vascular NAD(P)H oxidase to endothelial dysfunction in heart failure and the therapeutic effects of HMG-COA reductase inhibitor.Circ J,2004,68:1067-1075.

同被引文献9

  • 1谢秀梅,李志凌,马国添,李兢,方叶青.老年原发性高血压微量清蛋白尿的相关因素分析[J].中南大学学报（医学版）,2006,31(4):563-565. 被引量：1
  • 2Grundy SM,Brewer HB, Cleeman JI, et al. For the conference participants: Definition of metabolic syndrome. Report of the National Heart, Lung and Blood Institute/American Heart Association conference on scientific issues related to definition [J]. Circulation,2004,109:433-438.
  • 3Mathews DR, Hosker JP, Rudenski AD, et al. Homeostasis model assessment of insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man [ J ]. Diabetologia,1985, 28:412-419.
  • 4Cuspidia C, Meania S, Fusia V, et al. Metabolic syndrome and target organ damage in untreated essential hypertensives[J]. J Hypertens,2004, 22:1991-1997.
  • 5Leoncini G, Ratto E, Viazzli F, et al. Metabolic syndrome is associated with early signs of organ damage in nondiabetic, hypertensive patients[J]. J Intern Med, 2005, 257: 454-460.
  • 6Kahn R, Buse J, Ferrannini E, et al. The metabolic syndrome:time for a critical appraisal: Joint statement from the American Diabetes Assoiation and the European Association for the Study of Diabetes[J]. Diabetes Care,2005,28:2289-2304.
  • 7Khawk T, Wareham N, Bingham S, et al. Association of hemoglobinAlc with cardiovascular disease and mortality in adults:the European Prospective Investigation into Cancerin Norfolk[J]. Ann Intem Med,2004,141 : 413-420.
  • 8尹巧香,赵玉生.代谢综合征与心血管疾病[J].中华老年心脑血管病杂志,2003,5(6):421-422. 被引量：14
  • 9赵志钢,祝之明,李彦社.代谢综合征的颈动脉粥样硬化特征[J].中华内科杂志,2003,42(9):625-627. 被引量：38

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中国糖尿病杂志
2006年 第6期

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