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血浆前降钙素原对多发骨折感染并发症的预测 被引量:3

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摘要 目的研究动态监测血浆前降钙素原(proprocalcitonin,PCT)对多发骨折感染并发症的预测价值。方法多发骨折患者79例分感染、非感染两组于入院后的第1,3,5,7,10,14,21天收集血标本;对照组30例于入院后第1天收集血标本。应用LumitestPCT-Q试剂盒测定血浆PCT水平,ELISA法测定血浆C反应蛋白(CRP)水平。结果多发骨折患者非感染组与对照组相比血浆PCT水平轻度升高,CRP一直维持在较高水平,感染组患者所有指标均明显高于对照组(P<0.05)。感染组与非感染组相比,血浆PCT明显升高(P<0.05),而血浆CRP无显著差异(P>0.05)。分别以2.0μg/L、250mg/L为PCT、CRP的临界值预测感染,PCT的灵敏度、特异度、阳性预测值均明显高于CRP。结论血浆PCT是多发骨折患者并发感染敏感的预测指标,进行常规PCT检测有助于早期发现创伤后感染并发症,预测创伤的转归和预后。
作者 梁届东
出处 《中国骨与关节损伤杂志》 2006年第12期1005-1006,共2页 Chinese Journal of Bone and Joint Injury
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共引文献31

同被引文献19

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