摘要
[目的]探讨急性颈髓损伤后低钠血症的病因、发病机制、诊断和治疗。[方法]回顾性分析2004年-2006年收治的急性颈髓损伤后低钠血症患者15例的临床资料。[结果]全组患者入院24—72h内血钠低于130mmol／L，其中5例低于120mmol／L。14例尿钠40—68mmol／L，1例尿钠为148mmol／L；尿渗透压420～980mmol／L，12例患者经适当的补盐和限制水摄入量治疗，低钠症状2～3周内改善；2例发热患者因发热不能严格限制水摄入，其中1例2个月后恢复，另1例失访；1例患者补盐限水后病情加重，调整治疗方案后恢复。[结论]颈髓损伤越重，损伤后低钠血症发生率越高；颈髓损伤后低钠血症多由抗利尿激素分泌异常综合征引起；血钠浓度，血、尿渗透压等是诊断依据；适当补充钠盐和液体量是有效的治疗方法。
[ Objective ] To investigate the pathogenesis, pathology, diagnosis and therapy of hyponatremia after acute spinal cord injury. [ Method] Fifteen in-patients with hyponatremia after acute spinal cord injury from 2004 to 2006 were retrospectively analyzed. [ Result] Serum sodium was lower than 130 mmol/L in all cases. Urine sodiumcanned was from 40 to 68 mmol/L and urine osmotic pressure was from 420 to 980 mmol/L. After limitation of water intake and appropriate salt intake, 12 patients recovered at 2 to 3 weeks. Because of fever and avoiding limitation of water intake, the other 3 patients recovered slowly. [ Conclusion] The more serious the acute spinal cord injury, the higher the frequency of hyponatremia;syndrome of inappropriate antidiuretic hormone secretion（SIADH） is its primary cause： appropriate measures should be taken to correct the hyponatremia according to the findings of serum sodium and urine osmotic pressure.
出处
《中国矫形外科杂志》
CAS
CSCD
北大核心
2006年第24期1858-1859,共2页
Orthopedic Journal of China
关键词
颈椎
脊髓损伤
低钠血症
cervical vertebra
spinal cord injury
hyponatremia
