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雾化吸入前列腺素E_1在先天性心脏病并肺动脉高压中的应用 被引量:1

Effect of Prostaglandin E_1 in Inhalation in Children with Pulmonary Hypertension
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摘要 目的:评价雾化吸入前列腺素E1(PGE1)治疗先天性心脏病(CHD)并肺动脉高压(PH)的疗效。方法:雾化吸入PGE1治疗CHD并PH 20例;观察治疗前、后肺动脉平均压(PAMP)、肺动脉收缩压(PASP)、心脏指数(CI)以及Tei指数的变化。结果:本组PAMP、PASP、Tei指数比治疗前均有明显下降(P<0.01),外周血压、HR与治疗前比无统计学意义。结论:雾化吸入PGE1可使CHD并PH患儿肺动脉压力下降,心功能改善。 Objective: To assess inhalation of prostaglandin E1 (PGE1)in children with pulmonary hypertension(PH) secondary to congenital heart disease (CHD). Methods: Echocardiography was used to measure the pulmonary artery mean pressure(PAMP), pulmonary artery systolic pressure(PASP), cadiac index( CI) and Tei index in 20 patients. Resuits: PAMP, PASP and Tei index were obviously decreased after inhalation of PC, E1 ( P 〈 0.01). Conclusion: The inhalation of PGE1 may be the more convenient and safer way for the treatment of PH secondary to CHD.
出处 《汕头大学医学院学报》 2006年第4期213-214,共2页 Journal of Shantou University Medical College
基金 汕科府[2003]119号
关键词 肺动脉高压 前列腺索E1 雾化吸入 pulmonary hypertension prostaglandin E1 inhalation
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