摘要
目的探讨胃癌手术后早期肠内肠外营养(EN-PN)与完全肠外营养(TPN)的治疗效果。方法对2000年1月～2004年12月在我院普外科行胃癌根治术198例患者进行回顾性分析,其中97例(EN-PN组)采用术后早期肠内肠外营养治疗,101例(TPN组)采用完全肠外营养治疗,比较两组患者的术后营养指标(体重、血浆白蛋白、前白蛋白、视黄醇结合蛋白)、肛门排气时间、胃排空恢复时间、住院时间和总住院费、并发症发生率。结果EN-PN组术后第7天的血浆前白蛋白和视黄醇结合蛋白(302.54±58.65)g/L和(39.21±6.54)mg/L均显著高于TPN组的(236.89±48.84)g/L(P<0.05)和(25.36±5.37)mg/L(P<0.01);EN-PN组的肛门排气时间、胃排空恢复时间、住院时间分别为(56.8±7.1)小时、(6.6±3.8)天、(15.5±5.8)天,均显著少于TPN组的(79.6±14.6)小时(P<0.01)、(13.2±6.2)天(P<0.05)和(22.6±5.6)天(P<0.05);EN-PN组的并发症发生率18.6%和总住院费16568.35元均显著少于TPN组的40.6%(P<0.01)和28612.85元(P<0.01)。结论胃癌术后早期肠内肠外联合营养治疗安全可靠、简便易行、符合生理、肠功能恢复快、并发症少、费用低廉。
To investigate the therapeutic and social efficacies of enteral nutrition combined with parenteral nutrition （EN-PN） versus total parenteral nutrition （TPN） after gastric carcinoma surgery. Methods Ninety-seven patients with early EN-PN and 101 patients with TPN after gastric carcinoma surgery from January 2000 to October 2004 were retrospectively analyzed. Nutrition indexes, complications, recovery of gastrointestinal movement, length of hospital stay, and total heahhcare costs were analysed. Results Plasma prealbumin and retinal-binding protein in EN-PN group （302.54 ±58.65） g/L 和 （39.21 ±6.54） mg/L were significant higher than those in TPN group （236.89 ±48.84） g/L and （25.36 ±5.37） （P 〈0.05, P 〈0. 01 ） 7 days after surgery. Median days of the recovery of gastrointestinal movement in EN-PN group were significantly less than those in TPN group （P 〈 0.01, P 〈 0. 05）. Total complications in EN-PN group were significantly less than those in TPN group （ P 〈 0.01 ）. The costs in EN-PN group were significantly lower than those in TPN group （P 〈 0.01 ）. Conclusion Early enteral nutrition combined with parenteral nutrition after gastric carcinoma surgery is safe, simple, and physiologically feasible, with fast recovery of gastrointestinal functions,less complications, and relatively low costs.
出处
《中国临床营养杂志》
2006年第6期374-377,共4页
Chinese Journal of Clinical Nutrition
关键词
胃癌
肠内营养
肠外营养
gastric carcinoma
enteral nutrition
parenteral nutrition
