摘要
目的探讨地中海贫血孕妇血清中血清转铁蛋白受体与血清铁蛋白检测的临床意义。方法采用化学发光法检测40例地中海贫血孕妇和32例健康孕妇血清中可溶性转铁蛋白受体与血清铁蛋白水平。结果正常孕妇组和地中海贫血孕妇组血清转铁蛋白受体之间有显著性差异,血清铁蛋白无显著差异,而α-地贫组和β-地贫组间两者差异皆无显著性。结论血清转铁蛋白受体水平的增高与血清铁蛋白水平的降低可诊断地中海贫血孕妇缺铁的情况。
Objective To explore the clinical significance of detection of serum transferrin receptor （sTIR） and serum ferritin （SF） in diagnosis of thalasscmia in pregnant women. Methods The levels of serum transferrin and soluble transferring receptor in 40 thalassemia pregnant patients （observation group） including 20 cases with beta thalassemia trait and 20 eases with alpha thalassemia trait and 32 healthy pregnant subjects were determined with chemoluminiscence, Results Compared with that of the normal group values , the sTIR levels were significantly higher in thalassemia traits, but the concentrations did not show significant differences between beta thalassemia traits and alpha thalassemia traits . Conclusion Assay of sTIR and SF is useful for detection of condition of iron deficiency in pregnant thalassemia patients .
出处
《中国热带医学》
CAS
2006年第12期2173-2173,2176,共2页
China Tropical Medicine
