摘要
目前人类吞咽皮质中枢的定位仍不明确,限制了对吞咽周围器官病理生理学改变的了解和吞咽康复治疗的发展。动物实验发现,非人灵长目动物的运动前区皮质、感觉运动区、额叶、顶叶、颞叶岛盖、眶额皮质和扣带回皮质与吞咽功能相关。最近,人们利用功能磁共振成像、正电子发射体层摄影和脑磁图等先进的技术手段发现人类吞咽需要多个脑区参与,主要集中在主要感觉运动区皮质/前运动区、前扣带、岛叶和顶枕区。然而,各个脑区的具体功能和作用以及脑区之间的相互联系仍不清楚,还需要进一步研究来明确。
The localization of human swallowing cortical area remains unclear, which prevents the understanding of pathophysiologic change of peripheral swallowing apparatus and the development of swallowing rehabilitation. Animal experiments have found that the non-human primates, premotor cortex, sensorimotor area, frontal, parietal and temple operculum, orbitofrontal cortex and cingulate cortex are associated with swallowing function. Recently, by using the advanced techniques such as functional MRI, position emission tomography and magnetoencephalography, it was found that a ntanber of encephalic regions participated in the human swallowing, mostly concentrated in primary sensorimotor cortex, premotor cortex, cingule, insular lobe, and parietal-occipital area. However, the exact functions and roles of various encephalic regions and their correlations between various encephalic regions remain unclear. Further studies are needed to identify them.
出处
《国际脑血管病杂志》
2006年第10期774-777,共4页
International Journal of Cerebrovascular Diseases
关键词
吞咽
皮质中枢
功能定位
功能磁共振成像
swaUow, cortical arca
functional localization
functional mngnetic resorance imaging
