摘要
报告5例慢性苔藓样角化病。男4例,女1例,年龄13～50岁。3例皮损为带状或网状分布的紫红色丘疹,2例皮损呈疣状。皮损多无自觉症状,但有1例患者皮损伴有剧烈的瘙痒。组织病理改变主要为表皮角化过度伴局灶性角化不全,局部颗粒层增厚,棘层不规则肥厚,表现为棘层肥厚和萎缩相间,基底细胞液化变性。真皮浅层炎性细胞呈带状浸润,主要为淋巴细胞和组织细胞,并可见少量嗜酸性粒细胞和浆细胞。4例患者的毛囊和真皮血管周围也有炎性细胞浸润。本病需与扁平苔藓和扁平苔藓样角化病等鉴别。
Here five cases of keratosis lichenoides chronica are reported. One of them was female, the others were male, with the age from 13 to 50 years old. The lesions of three patients were consisted of lichenoid violaceous papules arranged in a linear or reticular pattern. In the other two patients the lesions coalesced into warty hyperkeratotic plaques. The lesions were asymptomatic, but in one patient it was associated with severe pruritus. Histopathologic examination demonstrated hyperkeratosis, focal parakeratosis, and irregular acanthosis which presented with the alternation of acanthosis and atrophy. The liquefaction degeneration of the basal cells was significant. In the upper dermis there was a band-like infiltration of cells which consisted of lymphocytes and histiocytes with a few eosinophilis and plasma cells. Perifollicular and perivascular cell infiltration was also noticed in four patients. KLC has to be differentiated with lichen planus and lichen planus-like keratosis.
出处
《临床皮肤科杂志》
CAS
CSCD
北大核心
2006年第12期769-771,共3页
Journal of Clinical Dermatology
关键词
角化病
苔藓样
慢性
临床组织病理分析
keratosis lichenoides chronica
clinicopathologic analysis
