摘要
目的对临床分离的４７５株酵母样真菌进行鉴定，调查与患者免疫状态及抗生素使用的关系。方法沙保弱培养基分离真菌，用ＶＩＴＥＫＡＭＳ６０做菌种鉴定并分类，应用免疫比浊法测定免疫球蛋白。结果４７５株酵母样真菌分为２１种，包括念珠菌属１１种，酵母菌属５种，孢子菌属２种，隐球菌属３种。结论临床酵母样真菌近年鉴定更趋完善。患者免疫功能低下。
ObjectiveToinvestigate475strainsoffungifromclinicalsamplesandsomeassociatedfactorssuchaspatients'immunalstateandusageofantibiotics,etc.MethodFungiwereculturedbysabowrandmediumandidentifiedonVITEKAMS60.Immunoglobulin(Ig)wasdetectedbyimmunotur┐bidimetry.ResultsTwentyonekindsoffungiwereisolatedfrom475samples.17patients(70.96%)haveinfectionoffungiinmultipleareas.Igvaluewasolwerthannormalatleastinoneitem.ConclusionsClinicalfungihavebeenidentified.Theassociatedforhighfunhgiisolationrateincludeimmuno-comkpromisedstate,applicationofimmunoinhibitoryagents,andlongtimeuseofmultipleantibiotics.
