摘要
对７９例腹水患者按结核性、非结核良性及恶性分为３组，同步检测腹水ＣＡ_（５０）及ＣＥＡ。结果恶性腹水中ＣＡ_（５０）、ＣＥＡ明显高于另两组（Ｐ＜０．０１）。ＣＡ_（５０）诊断恶性腹水的敏感性和特异性分别为７７．８％和９５％，且不受结核等渗出性腹水的影响，作为单项标记，其敏感性优于ＣＥＡ，若二者联合检测敏感性可进一步提高。
To investigate the differential diagnosis of ascites,the authors measured the concentrations of CA(50) and CEA in ascitic fluid of 79 patients simultaneously.The result showed that the level of both CA(50) and CEA in malignant ascites were significantly higher than that in tuberculous ascites and non-tuberculous benign ascites,P<0.01;as a single marker,the sensitivity and specifcity of ascitic CA(50) in the diagnosis of malignant ascites were 77.8%and 93%respectively,but the both of CEA were 52.8%and 93%respectively; Combined measurement of the both could improve the sensitivity significantly,with a little reduction of specificity. The study indicated that ascitic CA(50) and CEA were valuable markers,the evaluation of which was not affected by tuberculous ascited in the diagnosis of malignant ascites;CA(50) was a better marker than CEA in the diagnosis of malignant ascites;And combined measurement of the both could improve the sensitivity singnificantly.
出处
《南通医学院学报》
1996年第4期506-507,共2页
ACTA Academiae Medicinae Nantong
关键词
糖抗原50
癌胚抗原
恶性
腹水
诊断
Carbonhydrate Antigen(CA_(50))
Carcinoembryonic Antigen (CEA)
Malignant ascites
Diagnosis
