摘要
由氯化亚砜和棕榈酸制得棕榈酰氯．在100mL水-丙酮混合溶剂存在下，以棕榈酰氯和甘氨酸为原料合成了N-棕榈酰基甘氨酸钠，用正交实验法研究了影响反应的主要因素及其优先顺序，优化反应条件为n（棕榈酰氯）：n（甘氨酸）-1．0：1．5，反应温度为25℃，反应时间为3．0h，pH值为9～10，产物质量收率为90．579／6，并对N-棕榈酰基甘氨酸钠的应用性能进行了测定．
The sodium palmityl glycine（SPG） was synthesized from palmitoyl chloride and glycine with mixed solvent of water-acetone. The factors of its synthesis were studied in detail with orthogonal test. The optimum conditions were obtained as follows：the molar ratio of palmitoyl chloride： glycine = 1.0 ： 1.5 ,reaction temperature 25 ℃, reaction time 3.0 h ,pH 9- 10,the yield of SPG is 90.57%. The application properties of SPG were measured.
出处
《北京工商大学学报（自然科学版）》
CAS
2006年第6期9-12,共4页
Journal of Beijing Technology and Business University:Natural Science Edition
基金
河南省科技攻关项目(424270091)
