摘要
代谢综合征是一组代谢起源的、相互关联的、群集发生的危险因子。它们直接促进粥样硬化性心血管疾病和2型糖尿病的发生、发展。其首要处理目标是降低临床动脉粥样硬化疾病的风险。一线治疗应针对动脉粥样硬化疾病主要危险因子:吸烟、高低密度脂蛋白胆固醇(LDL-C)水平、高血压和糖尿病。其另一处理目标是预防2型糖尿病的发生。其处置重点应是通过生活方式的改变减轻可纠正的内在危险因子(肥胖、缺乏体力活动和致粥样硬化饮食)。
Metabolicsyndrome is a combination of interrelated risk factors of metabolic origin that appear to promote directly the devel-opment of atherosclerotie cardiovascular disease and type 2 diabetes mellitus.The primary goal of clinical management in subjects with meta-bolic syndrome is to reduce the risk of clinical atherosclerotic disease.First-line therapy is directed toward the major risk factors:cigarette smoking,excessive levels of LDL-C,hypertension,and diabetes mellitus.Prevention of type 2 diabetes mellitus is another important goal when it is not present in a subject with the metabolic syndrome.The main emphasis in the management of metabolic syndrome is to mitigate the modifiable underlying risk factors(obesity,physical inactivity,and atherogenic diet)through lifestyle changes.
作者
华琦
尹春琳(综述)
HUA Qi;YIN Chun-lin(Department of Cardiology,Xuanwu Hospital of Capital Medical University,Beijing 100053.China)
出处
《心血管病学进展》
CAS
2006年第6期688-691,共4页
Advances in Cardiovascular Diseases
关键词
代谢综合征
危险因子
心血管疾病
生活方式改变
metabolic syndrome
risk factor
atherosclerotic cardiovascular disease
lifestyle change
