摘要
以对叔丁基杯[4]芳烃(1)为原料,分别与1,2-二溴乙烷、1,3-二溴丙烷在碳酸钾的存在下进行选择性烷基化反应,生成杯[4]芳烃衍生物2和3．在氢氧化钠存在下,化合物2和3与过量的含不同官能团的2-巯基噻二唑反应,生成下缘含噻二唑基的杯芳烃衍生物4a-4c,5a-5c,其结构经1H．NMR,13C NMR,IR,MS和元素分析确证．
The p-tert-butylcalix[4]arene （1） was firstly alkylated with 1,2-dibromoethane and 1,3-dibromopropane to give calix[4]arene derivatives 2 and 3 in the presence of potassium carbonate, respectively. A series of p-tert-butylcalix[4]arene derivatives 4a-4c, 5a-5c which append thiadiazolidinyl groups at the lower rims were easily synthesized in good yields by the reaction of compounds 2 or 3 with 2-mercaptothiadiazole. All new compounds were characterized by ^1H NMR, ^13C NMR, IR, MS spectra and elemental analysis.
出处
《有机化学》
SCIE
CAS
CSCD
北大核心
2006年第11期1562-1565,共4页
Chinese Journal of Organic Chemistry
基金
国家自然科学基金(No.20475050)
河南省自然科基金(Nos.2004601012
0511020100)资助项目.
关键词
杯[4]芳烃衍生物
噻二唑
合成
表征
calix[4]arene derivative
thiadiazole
synthesis
characterization
