摘要
目的比较全身麻醉术中保留与不保留自主呼吸对老年口腔癌患者的影响。方法60例老年口腔癌病人随机分成两组,A组(n=30)麻醉诱导及术中不用神经肌肉阻滞剂,保留自主呼吸;B组(n=30),麻醉诱导及术中使用神经肌肉阻滞剂,不保留自主呼吸,行机械通气。观察两组麻醉诱导前(T0)、气管插管前(T1)、插管即刻(T2)、术中(T3)及术后(T4)的血压(BP)、心率(HR)、血氧饱和度(SPO2)及呼气末二氧化碳浓度(ETCO2)的变化。结果两组插管后即刻、B组插管前的血压、心率与麻醉诱导前比较差异明显(P<0.05),但术中及术后与诱导前比较无明显差异(P>0.05),A组术中呼吸末二氧化碳浓度高于B组(P<0.05),但术后低于B组(P<0.05)。A组术后血氧饱和度高于B组(P<0.05)。结论避免使用肌松药,保留自主呼吸,是保证老年口腔癌患者手术麻醉安全的有效措施。
Objective To compare the effect of the general anesthesia with spontaneous respiration to that of general anesthesia without spontaneous respiration in the operations of elder with stomatological cancer. Methods Sixty elder patients with stomatological cancer were randomly divided into two groups（n= 30 each）. Patients in group A didn＇t use neuromascular blocking agents and spontaneous respiration in induction of anesthesia and during the operation. Patients in group B used neuromascular blocking agents and pressure support. BP, HR, ETCO2 and SPO2 were recorded before ineduction of anesthesia（T0 ）,before intubation（T1 ）,immediately after intubation（T2） ,during operation（T3） and after operation（T4）. Results BP and HR were significantly increased immediately after intubation in group A（T2） and B（T2） as compared with baseline values（T0）. BP and HR were lower before intubation in group B（T1） as compared with baseline values（T0）. SPO2 was significantly higher in group A（T4） than in group B. during operation and after operation. ETCO2 was significantly higher in group A（T3） than that in group B. But ETCO2 was lower in group A（T4） than that in group B. Conclusion Don＇t use neuromascular blocking agents and spontaneous respiration during operation. It is a effective and safe method to let elder with stomatological cancer keep spontaneous respiraton during operation and anerthesia .
出处
《江西医学院学报》
CAS
2006年第5期121-123,132,共4页
Acta Academiae Medicinae Jiangxi
关键词
老年人
口腔癌
全身麻醉
呼吸
比较
aged
stomatological cancer
anesthesia, general
respiration
comparative study
