摘要
目的了解中老年妇女腰椎和髋部骨密度（BMD）的变化规律及其影响因素，探讨不同测量部位对骨质疏松（OP）诊断的影响，并为防治OP提供科学参考。方法从2004年1月～2006年1月在南昌大学第二附属医院骨密度测定窒检测的就诊者中随机抽取297例中老年妇女，准确记录其年龄、身高、体重；采用法国DMS公司Challenger双能X线骨密度测定仪（DEXA）检测腰椎（L2～4）、股骨颈、Ward’s三角以及大转子的BMD，然后进行比较和统计分析。结果各部位的BMD均随年龄的增加而下降，其中以Ward’s三角下降最为明显；腰椎（L2～4）和髋部各部位BMD均与身高、体重及体质指数（BMI）呈正相关；低BMI组（BMI％18）与超BMI组（BMI〉25）比较，髋部各部位的BMD差别有统计学意义（P〈0．01）；中老年妇女骨质疏松检出率最高者为腰椎，其次为Ward’s三角。结论中老年妇女是OP的高危人群，女性在40岁之后应监测BMD的变化，中老年人群应普及预防知识，加强锻炼，增加户外活动，以减少OP的发生。
Objective To investigate the change and influencing factors of bone mineral density （BMD） of lumbar spine and hip in middle-aged and aged females and to explore the effects of different measurement sites on the diagnosis of osteoporosis, providing the scientific reference for diagnosing and prevention osteoporosis. Methods Two hundred and ninety seven middle-aged and aged females were sampled randomly from the cases who were examined in the bone mineral density measurement department of The Second Affiliated Hospital of Nanchang University from January 2004 to January 2006, and their age（years）, stature（cm） and body weight（kg） were recorded exactly. The BMDof lumbar （L2-4）, femoral neck, Ward＇s and great trochanter was measured by dual energy X-ray absorptiometer（DEXA） ,then statistically analyzed. Results The BMD of above sites decreased with increasing of age, and the Ward＇s declined most obviously. The BMD of lumbar （L2-4） and all sites of hip had positive correlation with stature, body weight and body mass index （BMI）. There was a significant difference in hip BMD between lower BMI group（BMI〈18）and upper BMI group（BMI〉5）. The detectable rate of OP was the highest at lumbar in middle aged and aged females, and the second was Ward＇s. Conclusion The BMD of females should be monitored later on 40 years old. They need enhance the exercises and increase the outdoor activities for reducing the osteoprosis occurrence.
出处
《江西医学院学报》
2006年第5期89-91,94,共4页
Acta Academiae Medicinae Jiangxi
关键词
骨质疏松
骨密度
中老年妇女
osteoporosis
bone mineral density
middle-aged and aged female
