摘要
本研究应用单次四环素荧光标记观察了两种不同刚度接骨板内固定后板下皮质骨的骨吸收与骨形成状况。结果显示：１．接骨板内固定后，板下骨的骨吸收与骨形成均明显增加，但以骨吸收为主要代谢活动。２．增加的骨改建活动或起源于骨内膜面，或起源与骨外膜面，二者各自有着不同的发展走向。骨内膜面的骨改建活动可沿横向血管表面进入皮质骨，最后出现于皮质骨中央哈氏管表面。而骨外膜面的骨改建活动则由接骨板两侧沿皮质骨表层向接骨板中央延伸。３．高刚度接骨板固定后，骨改建活动增加以骨内膜面来源为主，为此皮质骨内骨吸收腔形成也较多。相反，低刚度接骨板内固定后，骨外膜面的骨改建活动较活跃，吸收腔多位于皮质骨外表层，皮质骨中央骨改建活动增加和骨质疏松形成均相对缓慢。
In this study, bone resorption and bone formation in cortex under the plates of varying stiffness were observed after a single tetracycline labelling was done. The results showed that after plate internal fixation both bone resorption and bone fomation activities were increased with predomination of bone resorption and that enhanced bone remolding appeared a directional development from early endosteal site to middle area of cortex by entering through transverse vessek. The early activated bone remolding in periosteal site extended from the marginal areas of the plate to the center beneath the plate.
出处
《医用生物力学》
CAS
CSCD
1996年第4期249-254,共6页
Journal of Medical Biomechanics
