期刊文献+

基于微型表面等离子共振生物传感器的葡萄糖浓度测量技术 被引量:6

Glucose Concentration Detecting Technology Based on Miniature Surface Plasmon Resonance Biological Sensor
在线阅读 下载PDF
导出
摘要 葡萄糖是生物体和食品中普遍含有的一种重要物质,其浓度的高低直接影响着生物体功能的正常发挥和食品的质量,因此检测葡萄糖的浓度有重要的意义和作用.本文利用微型表面等离子共振生物传感器构造了葡萄糖测量实验系统,并通过葡萄糖溶液浓度的测量实验对系统的性能进行了评估,对实验现象进行了分析,探讨了测量结果的数据处理方法.实验系统对葡萄糖溶液的分辨率达到了6.25mg/L,其精度高于其他采用折射率测量方法能够获得的葡萄糖溶液浓度的测量值.实验结果表明微型化的表面等离子共振测量装置在工业和医疗上的检测有很好的应用前景. Glucose is one of the most important components that contain in the body of organism and the food, the concentration of the glucose not only plays a significant role in exerting the normal function of organism but also in controlling the quality of food, thus to detect the concentration of glucose has important meaning. An experiment system is set up basing on a miniature surface plasmon biological senor to measure the concentration of glucose solution. The phenomenon of the experiment and the method for the data processing are analyzed, the lowest detection limit of this system reaches 6.25 mg/L, which is higher than other ways of refractive index measurement, the result shows a brilliant future for the application of SPR in industry and medical treatment.
出处 《传感技术学报》 CAS CSCD 北大核心 2006年第05B期2072-2076,共5页 Chinese Journal of Sensors and Actuators
关键词 微系统 表面等离子共振生物传感器 葡萄糖 浓度测量 GGBP蛋白 miniature system Surface Plasmon Resonance glucose concentration measurement GGBP
  • 相关文献

参考文献11

  • 1Matsubara K, Kawata S. Optical Chemical Sensor Based on Surface Plasmon Measurement[J]. Applied Optics, 1988, 27:1160.
  • 2Challener WA, Ollmann RR. Surface Plasmon Resonance Gas Sensor in a 'Compact Disc' Format[J]. Sensors and Actuators,B: Chemical 1999, 56(3):254-258.
  • 3Richalet-Secordel PM, Rauffer-Bruyeere N. Concentration Measurement of Unpurified Proteins Using Biosensor Technology under Conditions of Partial Mass Transport Limitation [J]. Analytical Biochemistry 1997,249(2) : 165-173.
  • 4Hubbard JB, Silin V. Self Assembly Driven by Hydrophobic Interactions at Alkanethiol Monolayers: Mechanism of Formation of Hybrid Bilayer Membranes[J]. Biophysical Chemistry 1998, 75(3):163-176.
  • 5Zeder-Lutz G, Zuber E. Thermodynamic Analysis of Antigen-Antibody Binding Using Biosensor Measurements at Different Temperatures[J]. Analytical Biochemistry 1997,246 (1): 123-132.
  • 6Melendez J, Carr R. A Commercial Solution for Surface Plasmon Sensing[J]. Sensors and Actuators, B: Chemical 1996,35(1-3) :212-216.
  • 7Nenninger GG, Piliarik M. Data Analysis for Optical Sensors Based on Spectroscopy of Surface Plasmons[J]. Measurement Science and Technology 2002,13(12) :2038-2046.
  • 8Stenberg E, Persson B. Quantitative Determination of Surface Concentration of Protein with Surface Plasmon Resonance Using Radiolabeled Proteins[J]. Journal of Colloid and Interface Science 1991, 143(2) :513-526.
  • 9Kurihara K, Nakamura K. Asymmetric SPR Sensor Response Curve-Fitting Equation for the Accurate Determination of SPR Resonance Angle[J]. Sensors and Actuators, B.. Chemical 2002, 86( 1 ):49-57.
  • 10Johnston KS, Yee SS. Calibration of Surface Plasmon Resonance Refractometers Using Locally Weighted Parametric Regression[J]. Analytical Chemistry 1997, 69(10): 1844-1851.

同被引文献80

引证文献6

二级引证文献23

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部