摘要
本工作用速率散射比浊法检测了64例脑血栓形成及56名健康人血清载脂蛋白A-Ⅰ和B(Apo A-Ⅰ,Apo B),并同时测定总胆固醇(Tch)、甘油三酯(TG)和高密度脂蛋白胆固醇(HDL-C)。脑血栓形成组ApoA-Ⅰ,Apo A-Ⅰ/Apo B和LDL-C/Apo B下降;TG、HDL-C/Apo A-Ⅰ升高,逐步判别分析示ApoA-Ⅰ是最好的判别指标。结果提示脑血栓形成患者血脂不但有量的异常,而且有质的异常;测定载脂蛋白优于检测血脂。
Serum apolipoprotein (Apo A-Ⅰ and Apo B) and lipid (Total cholesterol: Tch, Triglyceride: TG and HDL cholesterol: HDL-C) levels were measured in 64 patients with cerebral thrombosis and 56 healthy controls. Apo A-Ⅰ and Apo B were determined by a rate immunonephelometric assay. Apo A-Ⅰ and Apo A-Ⅰ /Apo B and LDL-C/Apo B were lower; TG and HDL/Apo A-Ⅰ were higher in patients. Stepwise discriminant analysis showed that Apo A-Ⅰ was the best discriminator. The results suggest that not only the quantitative abnormalities of lipids but also the compositional abnormalities of HDL and LDL particles are existent in cerebral thrombosis; determining the serum levels of apolipoproteins may be more useful than those of lipids.
出处
《第二军医大学学报》
CAS
CSCD
北大核心
1990年第6期531-534,共4页
Academic Journal of Second Military Medical University
关键词
脑血管病
脂类
脑栓塞
载脂蛋白
cerebrovascular disorders
lipids
cerebral embolism and thrombosis
apolipoproteins
rate immunonephelometric assay
