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白细胞干扰素喷雾治疗慢性宫颈炎的初步研究 被引量:22

A Preliminary Study on Therapeutic Effect of Human IFN-α on Chronic Cervicitis
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摘要 作者应用小剂量人脐血白细胞干扰素以随机双盲对照法对宫颈表面直接喷雾试治慢性宫颈糜烂215例,总有效率达93.02%,显效率以上达49.77%,与对照组相比有非常明显差异。根据作者的研究结果表明,宫颈糜烂的程度和类型与疗效有关。糜烂程度轻则治愈率高;三种类型的宫颈炎,以单纯型较易治,其显效率以上可达67.57%,其次是颗粒型(51.25%),最难治的是乳头型(26.23%)。此外,本文还讨论了干扰素治疗慢性宫颈炎的机制问题。 215 cases of chronic cervicitis were treated with low concentration interferon prepared from human umbilical cord blood by spray on the focus of the disease. A randomized double-blind and placebo-eontrolled trial was used in this study. The results obtained from the clinical study showed that the total effective rate of the treated-IFN group was 93.02% (200/215) and the markedly improved rate was 49.77% (107/215). There was very significant difference between the study group and the placebo-controlled group. It is indicated that the degree and type of chronic cervicitis is related to the therapeutic effect The erosion degree of cervix is slighter, it is easier for the treatment Chronic cervicitis is divided into three types. Among them, the simple type of chronic cervicitis is easily cured and its markedly improved rate was 67.57% (50/74). The second is particle type (51.25%, 41/80). The most difficult for treatment is papillar type (26.23%, 16/61). Moreover, the mechanism of treatment of chronic cervidtis with inteiferon is also discussed
出处 《第二军医大学学报》 CAS CSCD 北大核心 1990年第5期433-436,共4页 Academic Journal of Second Military Medical University
关键词 干扰素 宫颈炎 白细胞 喷雾治疗 interferon cervicitis randomized double-blind and placebo-controlled trial
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参考文献3

  • 1钱止维,实验和临床病毒学杂志,1987年,1卷,1期,60页
  • 2王淑贞,妇产科理论与实践,1985年
  • 3郑英,子宫颈疾病,1984年

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