摘要
目的 探讨阴道镜下多点活检与宫颈冷刀锥切对于宫颈上皮内瘤样病变Ⅲ级（CINⅢ）病理诊断的符合情况。方法 1995—2005年间对北京大学人民医院92例阴道镜下多点活检病理诊断为CINⅢ的患者进行宫颈冷刀锥切治疗，比较阴道镜下多点活检与宫颈冷刀锥切的病理结果之间的差异。结果 92例中有52例多点活检与冷刀锥切的病理结果一致，符合率为56．5％，40例多点活检与冷刀锥切的结果不同，其中11例多点活检诊断为CINⅡ／Ⅲ，而冷刀锥切诊断为微小浸润癌。结论 宫颈锥切是宫颈上皮内瘤样病变的一种重要诊断与治疗方法。阴道镜下多点活检病理提示宫颈上皮内瘤样病变Ⅲ级并伴随腺体受累可能是存在宫颈浸润癌的一个高危因素。人乳头瘤病毒（HPV）感染与宫颈病变有关，但未发现HPV高危型检测数值高低与患者病理级别之间的联系。
Objective To investigate the diagnostic differences on grade Ⅲ cervical intraepithelial neoplasia （ CIN Ⅲ ） between multiple biopsies （MB） and cold knife conization. Methods A total of 92 cases of CIN Ⅲ who underwent MB and CKC were chosen from 1995 to 2005 in the People＇s Hospital of Peking University, and the pathological differences were analysed. Results Fifty-two out of 92（56.5% ） cases had the same pathological reports between MB and CKC; 40 cases had different results. Eleven cases presented microinvasive cancer of cervix in CKC instead of CIN Ⅱ/Ⅲ in MB. Conclusion CKC is one of the important methods on diagnosis and treatment of cervical intraepithelial neoplasia. CIN Ⅲ accompanied with gland involved may be one of the markers of cervical invasive cancer, but results of high risk type detection of human papilloma virus （HPV） presente no relations to pathological grades.
出处
《中国实用妇科与产科杂志》
CAS
CSCD
北大核心
2006年第10期754-755,共2页
Chinese Journal of Practical Gynecology and Obstetrics
关键词
宫颈上皮内瘤样病变
冷刀锥切
Cervical intraepithelial neoplasia
Cold knife conization
