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瑞芬太尼和异丙酚在产科全麻中的应用 被引量:2

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摘要 目的应用瑞芬太尼和异丙酚施行产科全麻,观察其对新生儿和母体的影响。方法选择硬膜外麻醉有禁忌证、行剖宫产术患者32例,随机分成Ⅰ、Ⅱ两组,每组各16例。麻醉诱导插管Ⅰ组硫喷妥钠4~7mg/kg+氯胺酮0.5~1mg/kg+司可林1~2mg/kg。Ⅱ组瑞芬太尼1~1.5μg/kg+异丙酚1~1.5mg/kg+司可林1~2mg/kg。麻醉维持1%~2%氨氟醚吸入,0.08%司可林静脉滴注。胎儿娩出后μ组静脉加入芬太尼0.1~0.2mg,必要时间断静脉推注硫喷妥钠;Ⅱ组间断加入瑞芬太尼或/和异丙酚。记录术前胎儿心率、麻醉前、插管后即刻、手术10、20min时的心率(HR)、收缩压(SBP)、舒张压(DBP)、手术时间、手术开始至胎儿娩出时间,子宫收缩情况,术中失血量、术毕至拔管时间、新生儿出生后1、5、10min Apgar评分,术中知晓。结果Ⅰ组气管插管后HR、SBP、DBP均较术前增高,与术前比(P〈0.01)差异有显著性。增长率分别为HR27%、SBP22%、DBP21%。Ⅰ组气管插管后HR、SBP、DBP较Ⅱ组高,与Ⅱ组比P〈0.01差异有显著性。Ⅰ组术毕到拔管时间较Ⅱ组显著延长(P〈0.01)。其他观察指标差异无显著性。结论剖宫产全麻使用瑞芬太尼和异丙酚具有可行性,尤其是适合严重心血管合并症及重度妊高症患者。剖宫产全麻是否常规使用瑞芬太尼和异丙酚有待进一步研究证实。
出处 《四川医学》 CAS 2006年第10期1046-1048,共3页 Sichuan Medical Journal
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参考文献10

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