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异体和自体全厚关节软骨移植的实验研究 被引量:2

The experimental study on the allograft and autograft of full-thickness articular cartilage
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摘要 异体和自体新鲜全厚关节软骨移植共32只新西兰兔。异体移植有排斥反应,关节软骨完全吸收,缺损区被宿主新生软骨修复。自体移植的软骨完全有活力,植骨裂隙由新生软骨修复。关节软骨无再生能力,修复软骨来自骨髓松质骨的间充质细胞,术后控制性关节运动能促使软骨生长。新形成的软骨基质不及正常软骨基质质量好,甚至正常软骨与修复软骨间存在裂隙,不能完全融合。
出处 《中国临床解剖学杂志》 CSCD 北大核心 1996年第3期222-226,共5页 Chinese Journal of Clinical Anatomy
关键词 关节软骨移植 自体移植 异体移植 软骨移植 full-thickness of articular cartilage allograft auotgraft rabit
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参考文献1

  • 1唐宝悌,中华外科杂志,1991年,2卷,6期,89页

同被引文献17

  • 1郭世绂.关节软骨的形态、生理、生化特征及损伤修复[J].骨与关节损伤杂志,1995,10(1):61-64. 被引量:32
  • 2Noguchi T, Eyre DR, Koide S, et al. Repair of osteochonderal defects with grafts if cultured: hondrocytes[J].Clin Orthop,1994,302:251.
  • 3O'Driscoll SW, Keeley FW, Salter RB. The chondrogenic potential of free autogenous perosteal grafts for biological resurfacing of major full-thickness defects in joint surfaces under the influence of continuous passive motion[J].J Bone Joint Surg,1986,68A:1017.
  • 4Clark D, Harries M, Deter FK, et al. Tension studies of human knee ligaments-yield point, ultimate failure, and disruption of the cruciate and tibial collateral ligaments[J].J Bone Join Surg,1971,53A:1390-1391.
  • 5Meyer MN. Osteochondral transplantation[J].Surg Clin North,1978,58:429.
  • 6Brittbergm SN, Lindahi A, Nilsson A, et al. Treatment of deep cartilage defects in the kmee with artologous chondrocyte traslantation[J].Engl J Med,1994,331:889-895.
  • 7Van Susante JL, Buma P, Homminga GN, et al. Chondrocyte-seeded hydroxyapatite for repair of larg articular cartilage defects. Apilot study in the goat[J].Biomaterials,1998,19(24):2367-2374.
  • 8Shapiro F, Koide S, Glimcher MJ. Cell origin and differentiation in the repair of full-thickness defects of articular cartilage[J].J Bone Joint Surg (Am),1993,75:1508.
  • 9Kenneth LB, Richard L. Bone and cartilage transplantation in orthopaedic surgery-A review[J].J Bone and Joint Surg (Am),1982,64:270.
  • 10Noguchi T, Eyre DR, Koide S,et al. Repair of osteochonderal defects with grafts If cultured :hondrocytes. Clin Orthop 1994; 302:251

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