摘要
本文报告曲马多辅助硬膜外阻滞的对比观察。结果:(1)硬膜外阻滞辅用曲马多或曲马多加氟哌啶后(除牵拉胆囊时)HR、SBP、DBP、RR、SpO2均保持稳定,而辅用哌替啶加氟哌啶后SpO2均显著下降(P<0.01);(2)单用曲马多其镇静深度和抑制内脏牵拉反应的作用较差,但加用氟哌啶可增强镇痛镇静效果和提高抑制牵拉反应的发生率,并与哌替啶加氟哌啶的牵拉反应发生率比较无显著差异(P>0.05)。提示曲马多辅助硬膜外阻滞对呼吸循环无明显抑制,安全可靠。
According to the adjuvants used during epidural blockade,120 cholecystectomy patients were randomly allocated to three groups:group I,tramadol 2mg/kg iv;group Ⅱ,pathidine 1mg/kg plus droperidol 0 1mg/kg;group Ⅲ,tramadol 2mg/kg together with droperidol 0 1mg/kg.Results:A better analgesic and sedative effect was seen in group Ⅱ and Ⅲ.Conclusion:It is better to give tramadol as an adjuvant together with droptridol during epidural blockade and tramadol has less respiratomy and circulatory depression compared to pethidine.
出处
《临床麻醉学杂志》
CAS
CSCD
北大核心
1996年第4期195-197,共3页
Journal of Clinical Anesthesiology
关键词
硬膜外阻滞
曲马多
镇痛药
Epidural blockade Tramadol Pethidine Droperidol