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曲马多和氟哌利多辅助硬膜外阻滞对胆囊切除术牵拉反应的防治 被引量:7

Attenuation of Visceral Traction Reaction with Tramadol and Droperidol during Cholecystectomy under Epidural Blockade
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摘要 观察20例硬膜外阻滞下施行胆囊切除手术病人辅用曲马多和氟哌利多(曲氟合剂)对内脏牵拉反应的抑制效果,并与哌替啶和氟哌利多(哌氟合剂,n=20)或芬太尼和氟哌利多(芬氟合剂,n=20)比较。结果显示,曲氟合剂抑制内脏牵拉反应效果与哌氟、芬氟合剂相同,但曲氟组病人用药后SpO_2和RR变化轻微(P>0.05),哌氟组和芬氟组则显著下降(P<0.01),提示胸段硬膜外阻滞时辅用曲氟合剂较哌氟或芬氟合剂安全。 Attenuation of visceral response to surgical procedure with tramadol and droperidol (TD) was studied in 20 patients operated upon for cholecystectomy under epidural blockade, which was compared to that with either pethi- dine-droperidol (PD, n = 20) or fentanyl-droperidol (FD. n=20). It was found that TD was as effective as PD or FD in reducing visceral traction reaction during the operation. Respiratory depression shown by a decrease of SpO2 and RR was significantly less in TD group than that in PD or FD group. It is concluded that TD is effective as an adjuvant to epidural blockade and safer than PD or FD.
出处 《临床麻醉学杂志》 CAS CSCD 北大核心 1996年第3期132-134,共3页 Journal of Clinical Anesthesiology
关键词 曲马多 氟哌利多 硬膜外阻滞 胆囊切除术 Tramadol Pethidine Fentanyl Droperidol Epidural blockade
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