摘要
目的探讨慢性肺炎衣原体感染在急性缺血性脑血管病外周炎症反应中的作用。方法检测30例急性缺血性脑血管病患者和30例正常对照者血清肺炎衣原体特异性抗体(IgG),并检测其血清C反应蛋白(CRP)、血沉(ESR)及血中白细胞计数(WBC)。结果急性缺血性脑血管病患者外周炎症指标高于对照组(P＜0．01)。肺炎衣原体特异性抗体IgG阳性患者血清CRP水平、血沉、白细胞计数均高于阴性者(P＞0．05)。结论慢性肺炎衣原体感染参与缺血性脑血管病外周炎症反应,并与其他卒中因素共同引起急性期外周炎症指标水平升高。
Objective To evaluate a possible effect of chronic chlamydia pneumonia （Cpn） infection on peripheral inflammatory response of acute ischemic cerebrovascular disease. Methods Serum specific antibodies to chlamydia pneumonia （IgG） , C - reactive protein （CRP） level, erythrocyte sedimentation rate （ESR） and white blood cell （WBC） count were measured in 30 acute ischemic cerebrovascular disease patients and 30 controls. Results The levels of peripheral inflammatory markers （ CRP, ESR, WBC ） were higher in patients with ischemic cerebrovascular disease than in controls （ P 〈0.01 ）. The levels of CRP, ESR and WBC were higher in serum Cpn - IgG positive patients, compared with Cpn - IgG negative patients （ P 〉 0.05 ）. Condusion Chronic chlamydia pneumonia infection which plays a role in peripheral inflammation of acute ischemic cerebrovascular disease, and causes the increase of the levels of peripheral inflammatory markers complicated with other stroke factors.
出处
《中国急救医学》
CAS
CSCD
北大核心
2006年第10期650-652,共3页
Chinese Journal of Critical Care Medicine
关键词
肺炎衣原体
感染
炎症
脑缺血
Chlamydia pneumoniae
Infection
Inflammation
Cerebral ischemia
