摘要
目的探讨早发型重度子痫前期保守治疗的临床意义。方法回顾分析2004年8月-2005年12月。在我院住院并分娩的妊娠28—34周重度子痫前期病例56例，入院时均无严重的并发症及合并症，以终止妊娠前住院天数将病例分为保守治疗组及对照组。分析指标包括：终止妊娠孕周，孕周延长时间，孕妇并发症，新生儿体重及死亡率，剖宫产率。结果①对照组终止妊娠时间（224．18±12．31）d，保守治疗组平均延长妊娠时间为（11．83±7．63）d，终止妊娠时间（236．96±8．24）d，差异有显著性意义（P〈0．01）。②全部孕妇均痊愈出院，部分病例出现一个或多个并发症，对照组孕妇并发症发生率53．15％，保守治疗组58．33％，差异无显著性意义（P〉0．05）。③对照组新生儿平均体重（1．53±0．41）kg；保守治疗组新生儿平均体重（1．78±0．35）kg，差异有显著性（P〈0．05）。④对照组新生儿死产率31．25％，保守治疗组新生儿死产率12．15％，两组相比差异有显著性（P〈0．01）。⑤对照组剖宫产率59．36％，保守治疗组剖宫产率79．17％，两组相比差异有显著性意义（P〈0．01）。结论早发型重度子痫前期在适当挑选病例、加强监护条件下，保守治疗是可行的。
Objective To investigate the clinic significance of expectant management for patients with early onset of severe preeclampsia. Methods A retrospective analysis of 56 women with severe preeclampsia at 28 to 34 weeks from Aug,2004 to Dec, 2005 was performed. Patients were divided into two groups, conservative management group and control group, by hospital days before termination of pregnancy. Analytic index included gestational weeks of termination of pregnancy, complications of gravida, body weight of neonate and incidence of neonatal mortality as well as the incidence of uterine - incision delivery. Results ①The average prolongation of gestation of the conservative management group was （ 11.83 ± 7.63 ） days and the conservative management group had a longer average period of termination of pregnancy （236. 96 ± 8.24） days vs （224. 18 ± 12. 31 ） days, P 〈 0. 01. ②The two groups had similar incidences of complications of gravida （53.15% vs 58.33%,P 〉0. 05 ）. ③The conservative management group had a higher birth weight （1.78 ± 0. 35 ）kg vs （1.53 ± 0. 41 ） kg, P 〈 0. 05, ④significantly lower incidence of neonatal mortality （ 12. 15% vs 31.25%, P 〈0. 01 ） and ⑤significantly higher incidence of uterine - incision delivery （79. 17% vs 59. 36%, P 〈0. 01 ）. Conclusion It is feasible for expectant management of early onset of severe preeclampsia under intensive care and appropriately selected cases.
出处
《医药论坛杂志》
2006年第18期18-20,共3页
Journal of Medical Forum
关键词
子痫前期
早发
治疗
妊娠结局
Preeclampsia
Early onset
Therapy
Pregnancy outcome
