摘要
目的:观察低分子量肝素联用噻氯匹啶和单用噻氯匹啶治疗不稳定心绞痛(UAP)的临床疗效。方法:将59例UAP随机分为治疗组30例和对照组29例,疗程1周。结果:治疗组总有效率为83.33%,对照组为58.62%(P<0.05)。随访3个月对照组2例发生急性心肌梗死,治疗组1例。两组未发现明显不良反应。结论:在常规治疗基础上加用低分子量肝素能更有效地控制心绞痛发作,减少心肌梗死发生率。
Objective：To compare the effects of low molecular weight heparin （LMWH） combined with ticlopidine and ticlopidine alone on transient myocardial ischemia and in-hospital prognosis in patients with unstable angina pectoris （UAP）.Methods：59 patients with UAP were randomized into a control group receiving ticlopidine and another treatment group receiving ticlopidine plus LMWH for one week.Results：The effective rate was 83.33% in the LMWH group and 58.62% in ticlopidine group after one week （P〈0.05）.During the following-up of three months period,two cases developed acute myocardial infarction in ticlopidine group and one cases developed acute myocardial infartion in the treatment group.No obvious adverse reaction was observed in the both groups.Conclusion：On routine treatments,treatment with ticlopidine plus LMWH is more efficient than ticlopidine alone during the acute stage of UAP and treatment with LMWHs is efficient,safe and convenient.
出处
《现代医药卫生》
2006年第22期3416-3417,共2页
Journal of Modern Medicine & Health
关键词
低分子量肝素
噻氯匹啶
不稳定型心绞痛
Lowmolecularweight heparin（LMWH）
Ticlopidine
Unstable angina pectoris
