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首发精神分裂症血液流变学改变 被引量:4

STUDY OF THE HEMORHEOLOGY CHARACTERISTICS OF THE FIRST-EPISODE IN PATIENTS WITH SCHIZOPHRENIA
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摘要 目的探讨首发精神分裂症病人的血液流变学特征。方法选取60例首发精神分裂症病人,根据阳性症状量表(SAPS)和阴性症状量表(SANS)评分分为Ⅰ型和Ⅱ型,于治疗前后进行血液流变学检查。将结果与40名正常健康人血液流变学检查结果作对照。方法Ⅰ型精神分裂症病人的全血粘度、红细胞电泳指数比Ⅱ型明显增高(P<0.01);晚发组与早发组除血浆粘度、血沉外,其他指标均明显高于正常健康人指标(P<0.01);长病程组全血粘度、血浆粘度比短病程组明显增高(P<0.01)。结论血液高粘滞现象作为精神分裂症的生物学指标,对其诊断、治疗和转归判断具有一定的指导意义。* Objective To Study the hemorheology characteristics of the first - episode in patients with schizophrenia. Methods 60 first - episode inpatients with schizophrenia were selected and divided into Ⅰ and Ⅱ type group , first - episode and late episode group,long and short course group according to the schizophrenia type onset age and episode course. 40 normal persons were selected as control. Results The whole blood viscosity, red blood cell electrophoresis indexes of the Ⅰ type group were higher than those of the Ⅱ type group. Other index of the late group and the early group were higher than normal persons, except plasma viscosity and ESR. The whole blood viscosity, plasma viscosity of the long course group were higher than those of the short course group. Conclusion Blood hypervisemia biology index may play a role in diagnosis,treatment and prognosis of schizophrenia.
作者 陈燕梅
出处 《青海医学院学报》 CAS 2006年第3期181-184,共4页 Journal of Qinghai Medical College
关键词 精神分裂症 血液流变学 Schizophrenia Hemorheology characteristics
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