摘要
目的:探讨乙型病毒性肝炎肝硬化患者健康相关生活质量,并分析其影响因素。方法:采用简明生命质量测定量表(SF-36)中文版对120例乙肝肝硬化患者的生活质量进行测量,对其影响因素进行单因素分析和多因素logistic回归分析,并与正常人群进行对比。结果:除心理功能维度外,肝硬化患者生活质量各维度均低于对照组(P<0.001);Child分级主要影响生理健康方面的评分,而性别对生理及心理健康方面评分均有影响。结论:肝硬化患者生活质量普遍下降,其主要影响因素为性别与Child分级。
Objective： To explore factors associated with health-related quality of life （HRQOL） in patients with HBV-related liver cirrhosis. Methods： A cross-sectional study in which 120 patients＇ demographic and clinical characteristics were documented and their HRQOL was conducted by using the Chinese version of Short Form-36. The association of HRQOL impairment with clinical parameters was compared between patients and normal persons by univariate analysis and multiple logistic stepwise regression. Results： In all except one domains （mental health） of SF-36, HRQOL scores were significantly lower in the patient group than in the control group （ P 〈 0.001 ） ; Child class was mainly associated with score in Physical Component Summary （PCS） while gender affected both PCS and Mental Component Summary （MCS） score. Conclusion： HRQOL of patients with liver cirrhosis is impaired obviously. The score is further affected by gender and Child class.
出处
《山东大学学报（医学版）》
CAS
北大核心
2006年第9期885-888,共4页
Journal of Shandong University:Health Sciences
