摘要
目的了解山东省嘉祥县地方性氟中毒流行现状。方法采用流行病学抽样调查方法,对嘉祥县的郭庄等7个地方性氟中毒病村的居民饮水含氟量、8～12岁儿童氟斑牙检出情况、25岁以上成人临床与X线氟骨症检出情况及8～12岁儿童与成人尿氟水平进行调查。结果7个病村饮水含氟量有6个超过国家标准(≤1．0 mg/L),最高者达9．67 mg/L；8～12岁儿童及成人尿氟几何均值平均分别为3．52、4．49 mg/L,均明显超过正常上限值(1．50 mg/L)；8～12岁儿童氟斑牙检出率平均为73．1%,缺损率21．3%,氟斑牙指数1．60,病情最重的郭庄村氟斑牙检出率达93．9%,缺损率和氟斑牙指数分别为53．7%、2．45；对94例25岁以上成年人进行临床检查与X线拍片,临床氟骨症检出率及X线阳性检出率均为53．2%,并出现2例临床3度与8例X线Ⅲ期氟骨症患者,病情以郭庄村最重,氟骨症阳性检出率高达78．9%。结论嘉祥县地方性氟中毒病情仍然较重,尚未达到有效控制要求,应加大防治工作力度,以期早日摆脱高氟危害。
Objective To investigate the prevailing status of endemic fluorosis in Jiaxiang, a county in Shandong Province at present. Methods By using epidemiological sampling method, such idexes of endemic fluorosis as content of water fluoride in the local residents, the state of dental fluorosis among the children aged from 8～12 years old, the situation of skeletal fluorosis of clinic and X-ray among people above 25 years old, the concentration of urine fluoride were investigated in Guozhuang village and other six fluorosis villages of Jiaxiang county. Results Content of water fluoride were beyond the country standard （ ≤1.0 mg/L） in 6 of the 7 fluorosis villages, with the highest value being 9.67 rag/L; The geometric mean of urine fluoride were 3.52 and 4.49 mg/L, respectively in children aged from 8 ～ 12 years old and people 25 years old above, both were higher than the normal upper limit（1.50 mg/L） of urine fluoride; The rate of dental fluorosis and defect, and dental fluorosis index were 73.1%, 21.3% and 1.60, respectively among the children aged from 8～12 years old in the 7 villages mentioned above, Guozhuang is the most serious village with a dental fluorosis rate 93.9%, and a dental fluorosis index 2.45; In 94 adults over 25 years investigated, the prevalence rate of skeletal fluorosis, of both X-ray and of clinic were 53.2%, and 2 Ⅲ-degree clinical osteofluorosis and 8 Ⅲ-degree X-ray osteofluorosis were found, the most serious village was Guozhuang with prevalence rate 78.9%. Conclusions In Jiaxiang County, endemic fluorosis is still very serious and out of control. So the government should strengthen the work of control as quickly as possible.
出处
《中国地方病学杂志》
CAS
CSCD
北大核心
2006年第5期537-540,共4页
Chinese Jouranl of Endemiology
关键词
氟化物
中毒
饮水
流行病学研究
Fluorides
Poisoning
Drinking
Epidemiologic studies
