摘要
目的探讨妊娠合并血小板减少症的病因及治疗。方法对128例妊娠合并血小板减少患者的临床资料进行回顾性分析。结果单纯由妊娠引起的血小板减少91例(71.09%),特发性血小板减少性紫癜(ITP)引起11例(8.59%),合并肝脏疾病10例(7.81%),重度妊高征引起14例(10.94%),Rh血型不合及病毒感染各1例(各占0.78%)。对血小板(50×109/L者用强的松治疗,分娩前后使用血小板制剂,同时考虑剖宫产。结论妊娠期血小板减少是最常见的妊娠合并血小板减少症类型。有合并症的血小板减少程度严重,大多<70×109/L,半数ITP有临床症状。糖皮质激素是治疗严重血小板减少的有效手段,术前血小板仍<50×109/L可输注浓缩血小板。
Objective： To explore the causes and therapy of pregnant women with thmmbocytopenia. Methods： 128 cases with thrombocytopenia were reviewed. Results： Thrombocytopenia was mainly caused by prenacy- associated thrombocytopenia （PAT） in 91 （71,09%） cases, idiopathic thrombocytopenia （ITP） in 11 cases （8.59%）, hepatic disease in pregnancy in 10 （7, 81% ） cases, pregnancy induced hypertension 14 （10, 94% ） cases, Rhesus isoimmunization and viral infection each 1 （0.78% ） case. Prednisone was considered if the platelet count was less than 50×10^9/L, Platelet transfusion was given to those with platelet count less than 50 ×10^9/L before and after delivery. If the platelet count was less than 50×10^9/L esarean delivery might be performed. Conclusion： PAT is the most common type of thrombocytopenia during pregnancy. Degree of thrombocytopenia with complication was more severe （platelet count usually less than 70×10^9/L）. Half of ITP are symptomatic. Glucocorticoid is effective treatment for severe thrombocytopenia. Platelet transfusion may be considered when platelet count is still less than 50 ×10^9/L before opreation.
出处
《中国优生与遗传杂志》
2006年第9期71-72,共2页
Chinese Journal of Birth Health & Heredity
关键词
妊娠
血小板减少
Pregnancy
Thrombocytopenia
