摘要
Objective： To investigate tumor necrosis factor （TNF） of lung the regulation of acupuncture on γ-interteron （LNF-γ） and cancer-operative cases. Methods： to determine the INF-γ and TNF contents in the blood serum of lung cancer patients by double antibody sandwich immunoenzymatic method （ELISA）; to measure the INF-γ and TNF contents of 30 lung cancer patients in the acupuncture anesthesia group and 30 lung cancer patients in general anesthesia group before the operation and at the 8th days, the 12th day after the operation respectively and make comparison between the two groups. Results. The pre-operation INF-γ contents of the two groups showed no significant difference （P〉 0.05）; the post operation INF-γ contents of the two groups showed significant difference at 8th day and 12th day after the operation （P〈 0.05）; the acupuncture anesthesia group was superior to the general anesthesia group; the self-comparison of the anesthesia group showed significant difference at the 12th day and 8th day after the operation （P〈 0.05）; the pre-operation TNF contents of the two groups showed no significant difference （P〉 0.05） and the post-operation TNF contents of the two groups showed significant difference at the 8th day and 12th day after the operation （P〈 0.05）. Conclusion：Acupuncture can increase the serum INF-γ and TNF contents of lung cancer patients and therefore regulate the immunity of the patients.
目的:探讨肺癌手术患者应用针刺对γ-干扰素(INF-γ)和肿瘤坏死因子(TNF)的调节。方法:采用双抗体夹心免疫酶标法(EUSA)检测肺癌患者血清中 INF-γ和肿瘤坏死因子含量;将针药麻组与全麻组肺癌手术患者各30例,分别在术前、术后8日、术后12日测量 INF-γ和 TNF 含量作比较。结果:血清中 INF-γ含量在术前作两组比较无明显差异(P>0.05)。术后第8日和第12日作两组比较均有显著差异(P<0.05),针药麻组优于全麻组。自身比较针药麻组术后第12日和术后第8日比较有显著差异(P<0.05)。血清中肿瘤坏死因子含量在术前作两组比较(P>0.05)无明显差异:在术后第8日及术后第12日作比较(P<0.05)均有显著差异。结论:肺癌手术患者应用针刺能升高血清中 INF-γ和 TNF 含量,对肺癌手术患者有免疫调节功能。
