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γ─氨基丁酸在人体耳蜗的定位 被引量：3

Localization of gama-aminobutyric acid in the human cochlea
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摘要 应用免疫细胞化学方法，研究γ－氨基丁酸（ＧＡＢＡ）在人体耳蜗的定位。结果表明：ＧＡ－ＢＡ定位于人体耳蜗传出神经系统；是人体耳蜗传出神经递质。 The localization of gama-aminobutyric acid(GABA ) in the human cochlea was studied with the method of immunocytochemistry. It was found that GABA-like immunoreactivity was confined to the efferent systems of the human cochlea.The result demonstrates that GABA is an efferent neurotransmitter in the olivocochlear systems of human cochlea.
作者 孔维佳
机构地区 武汉同济医科大学附属协和医院耳鼻咽喉科
出处 《临床耳鼻咽喉科杂志》 CSCD 1996年第6期323-325,共3页 Journal of Clinical Otorhinolaryngology
关键词 Γ-氨基丁酸 耳蜗 免疫细胞化学 传出神经系统 Gama-aminobutyric Acid Cochlea Human Immunocytochemistry
分类号 R322.92 [医药卫生—人体解剖和组织胚胎学] R322.85 [医药卫生—人体解剖和组织胚胎学]
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  • 1刘军,孙勍,韩冰,孙建和,于宁,李兴启.尼福地平对豚鼠耳蜗功能和噪声性听力损失的影响[J].中国耳鼻咽喉头颈外科,2006,13(4):232-236. 被引量：9
  • 2丁大连,Richard Salvi.氨基糖苷类抗生素耳毒性研究[J].中华耳科学杂志,2007,5(2):125-131. 被引量：47
  • 3Tabuchi K,Tsuji S, Asaka Y, et al. Ischemia--reperfusion injury of the cochlea: effects of an iron chelator and nitric oxide synthase inhibitorts[J]. Hear Res, 2001,160 : al.
  • 4Rao D, Fechter LD. Protective effects of phenyl--N--tert-- butylnitrone on the potenliation of noise--induced bearing loss by carbon monoxide[J]. Toxicol Appl Pharmacol, 2000,67: 125.
  • 5Seidman MD. Effects of dietary restriction and amioxidants on presbyacusis[J]. Laryngoscope, 2000,110: 727.
  • 6Husain K, Whitworth C, Somani SM. Carboplatin induced oxidative stress in rat coehlea[J]. Hear Res, 2001,159:14.
  • 7Tanaka C, Chen GD, Hu BH, et al. The effects of acoustic environment after traumatic noise exposure on hearing and outer hair cells[J]. Hearing Research, 2009,250: 10.
  • 8Nancy GH, Sandra LM, Henderson D, et al. Noise-induced hearing loss in chinchillas pre--treated with glutathione monoethylester and R-- PIA[J]. Hearing Research, 2003, 179:21.
  • 9Sha SH, Schacht J. Salicylate attenuates gentamicin--induced ototoxieity[J]. Laboratory Investigation, 1996, 79: 807.
  • 10Sha SH, Taylor R, Forge A, et al. Differential vulnerability of basal and apical hair cells is based on intrinsic .susceptibility to free radicals[J]. Hearing Research, 2001,155 : 1.

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临床耳鼻咽喉科杂志
1996年 第6期

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