摘要
在国内首次报道细胞间粘附分子和血管细胞粘附分子与增殖型糖尿病性视网膜病之间的关系。结果表明，在糖尿病视网膜病变组织中，细胞间粘附分子的阳性率为９０％（３６／４０）；血管细胞粘附分子为８０％（３２／４０）。阳性细胞主要为淋巴细胞，此外，还有纤维母细胞，视网膜色素上皮细胞及新生血管内皮细胞。细胞间粘附分子和血管细胞粘附分子在糖尿病视网膜病变组织中的表达。提示细胞与细胞间的相互作用以及免疫反应在增殖型糖尿病性视网膜病的发生发展中起重要作用。
Using monocolonal antibody,the expression of C erbB 2 oncoprotein was detected by immunohistochemistry in 84 cases of invasive ductal carcinoma of the breast.Through analysis on comparison of the C erbB 2 expression and follow up data,the results showed:(1) C erbB 2 expression rate was 55.9%(47/84).(2) no relativity was found between C erbB 2 expression and tumor's TNM stagas,recurrence,distant metastases and the 5 year survival rate( P >0.05),C erbB 2 expression was only related with metastasis of axillary lymphnodes and 2 year mortality.(3) C erbB 2 expression was not related with the prognosis in cases both with positive or negative lymph nodes.The conclusion of this study is that C erbB 2 expression could not be used as a prognostic predictor in invasive ductal carcinoma of the breast.
出处
《中山医科大学学报》
CSCD
1996年第3期185-189,共5页
Academic Journal of Sun Yat-sen University of Medical Sciences
基金
国家教委资金资助
关键词
胞间粘附分子
糖尿病
视网膜病变
免疫学
carcinoma,ductal/pathology
breast neoplasms/pathology
neoplasm proteins
immunohistochemistry
prognosis
