摘要
采用抗牛乳头瘤病毒（ＢＰＶ），癌胚抗原（ＣＥＡ）免疫组化技术及核仁组成区相关蛋白（ＡｇＮＯＲｓ）银染方法对１０１例尖锐湿疣（ＣＡ）和１２例宫颈鳞癌进行病理观察。结果ＣＡ的ＢＰＶ表达明显高于宫颈鳞癌；ＣＡ的ＣＥＡ阳性表达与宫颈鳞癌有显著性差异，而ＣＡ的不典型增生型其ＣＥＡ表达（弱阳性）与宫颈鳞癌则无显著性差异；ＣＡ的ＡｇＮＯＲｓ计数分布除不典型增生型外，其余各组与宫颈鳞癌有显著性差异。提示ＣＡ大多数为良性增生性病变，而不典型增生型有恶性发展的倾向．
Argyrophil methed for Nucleolar Organizer Regions(AgNORs)and immunohis-tochemistry of Bovine Papillomavirus(BPV)and Carcinoma Embryo Antigen(CEA)were usedfor analysing 101 cases of Condyloma Acuminata(CA)and 12 cases of cervlal squamous carcino-ma(CSC).The BPV positive expression in CA is much higher than that in CSC.This may berelated to the fact that the virus in the canaerous tissue integrate tbemselves into the genome ofthe cancer cells. The CEA positive rate in CA is significantly different from that in CSC.TheAgNORs count in CA(except the atypicat proliferative type)is significantly different from thatin CSC.The results show that most of CA are benign proliferative lesions of the epithelium.But,the atypical prplifertive type of CA may progress into amlignancy.
出处
《广西医科大学学报》
CAS
1996年第2期49-52,共4页
Journal of Guangxi Medical University
关键词
尖锐湿疣
AGNORS
免疫组化
condyfoma acuminata
bovine papillomavirus
carcinoma embryo antigen
nucleoarorganizer rebions
