摘要
以三种标准菌株定量污染颗粒状骨移植物，分别做染菌载体冻干前后γ射线辐照及环氧乙烷（ＥＯ）气体消毒试验，结果显示未冻干时环氧乙烷气体比γ射线有更快更强的灭菌效果；冻干使染菌骨粒活菌含量无明显减少，却使细菌对γ射线特别是ＥＯ抗性大大增加，提示临床消毒骨移植材料时应注意冻干的影响。纯的ＥＯ气体用于颗粒状骨移植物消毒效果满意。
Thebonegraftswereexperimentalycontaminatedwith107cfu/mlbacteriaofStaphylo-coccusaureus,BacilussubtilisglobigiandBaciluscereus,andfreeze-dried,beforesterilizationwithvariousdosesofgaseousethyleneoxide(EO)or60Cobaltgammaradiation.Theprocessoflyophiliza-tioncouldnotdecreasethenumberofthebacteriainthebonegraftsdistinctlybutincreasetheirresis-tancetoEOandgammaradiation.ThemicrobiocidalpropertiesofgaseousEOwerestrongercompairedwithgammaradiation,andthemoderatedoseofEOforsterilizationoftheparticulatebonegraftsisde-sirable.
出处
《中华骨科杂志》
CAS
CSCD
北大核心
1996年第8期492-494,共3页
Chinese Journal of Orthopaedics
关键词
骨移植材料
灭菌
冻干
BonegraftSterilizationLyophilizationEthyleneoxideRadiation,Ionizing
