摘要
应用免疫组织化学方法$检测肾上腺嗜铬细胞瘤及瘤旁肾上腺组织中γ-干扰素（INF-γ）样物质的表达。在16例肾上腺嗜铬细胞瘤的瘤细胞浆中,有15例存在1FN-γ样免疫反应阳性物;在26例瘤旁肾上腺组织中仅2例在网状带细胞浆内有IFN-γ免疫反应阳性物。提示 IFN-γ样免役反应物可能是一种与分化有关的抗原。
Expression of gamma interferon (IFN-γ)-like substance in adrenal pheochromocytoma was investigated with immunohistochemical technique. In 15 out of the 16 cases of adrenal pheochromocytoma positive IFN-@-like immunoreactive substance was detected in the cytoplasm of the tumor cells, whereas in adrenal tissues adjacent to adrenal tumors in 26 cases (pheochromocytoma 12, adrenal corti-col tumors 12, others 2) only two with pheochromocytoma showed positive IFN-γ-like immunoreactive substance in the cytoplasm of zona reticularis cells. The results suggest that IFN-γ may be a kind of antigen associated with differentiation of cell.
出处
《中华内分泌代谢杂志》
CAS
CSCD
北大核心
1996年第2期90-92,共3页
Chinese Journal of Endocrinology and Metabolism
关键词
Γ干扰素
嗜铬细胞瘤
表达
Interferon-γ Pheochromocytoma, adrenal
