摘要
用Ｓ－１００蛋白质抗体对７１例不同预后的大肠癌患者原位癌组织进行ＡＢＣ免疫组化染色。结果表明术后生存期≥５年者癌组织Ｓ－１００＋树突状细胞ＤＣ）数量明显高于术后生存期＜５年者（Ｐ＜０．００１）。在具有同一种病理因素的患者中，生存期不同者其癌组织ＤＣ数量差异有显著性。揭示癌组织ＤＣ数量可作为估计患者预后的指标之一。
Dendritic cells (DC) in paraffin-embeded tissue were measured with ABC immunohistochemial method using S-100 protein antibody from 71 cases of colorectal carcinomas. Quantitative analysis showed that the patients who survived longer than 5 years had significantly higher DC number in primary tumor than those less than 5 years (P<0.001). Irrespective of othet morphologic fectures, there was a statistically significant difference between two groups (P<0.01). The results suggests that the amount of DC in situ might be used as an indicator in assessing prognosis of colorectal carcinoma.
出处
《实用肿瘤杂志》
CAS
北大核心
1996年第5期211-213,共3页
Journal of Practical Oncology
