摘要
目的:探讨儿童肾癌的临床特征及诊治方法。方法:回顾性分析2例儿童肾癌患者的临床资料。1例临床表现为间断无痛性肉眼血尿2年,CT示左肾有12cm实性肿物,不均匀强化。1例外伤后左肾周出现血肿,以左肾破裂出血行左肾切除术。检索PubMed和CBM数据库相关文献进行复习。结果:2例均行手术治疗,术后病理检查报告为肾透明细胞癌,Robson分期分别为Ⅲ期和Ⅰ期。1例术后接受干扰素-α治疗。术后随访13及33个月未见肿瘤复发及转移。结论:儿童肾癌临床上罕见,应与肾母细胞瘤等相鉴别。治疗以手术为主,辅助治疗的疗效有待于进一步研究。
Objective：To study the clinical features, diagnosis and treatment of renal cell carcinoma in children. Methods：Two cases of renal cell carcinoma in children （1 male, 1 female; both 12 years） were reported. The first case presented with intermittent gross hematuria for two years. CT revealed a solid mass of 12cm in diameter in the left kidney with uneven enhancement after contrast administration. The other case presented with rupture of kidney. The Pubmed and CBM databases were searched for related articles, and the clinical data were reviewed. Results：Both patients received left radical nephrectomy. Pathological examination confirmed renal cell carcinoma. Disease stages were stage Ⅲ and stage Ⅰ respectively. The first case received adjuvant interferon therapy. There was no evidence of recurrence and metastasis during the follow-up of 13 and 33 months respectively, in each case. Conclusions： Renal cell carcinoma in children is rare, it should be distinguished from Wilms tumors. Surgery is the main therapy. The role of adjuvant therapy should be defined more clearly.
出处
《临床泌尿外科杂志》
2006年第9期662-664,共3页
Journal of Clinical Urology
关键词
肾肿瘤
腺癌
儿童
Kidney neoplasms
Carcinoma
Child
