摘要
目的探讨小儿孤立性血尿的病理类型。方法对符合孤立性血尿诊断标准的23例患儿,行B超定位引导,局麻或全麻后,采用负压吸引行小儿经皮肾活检;肾穿标本用特制邮寄盒远程送检,肾组织进行光镜、电镜及免疫组织化学检查。结果膜性增生性肾小球肾炎(MsPGN)8例(34.9%),微小病变性肾病(MCN)5例(21.7%),IgA肾病(IgAN)4例(17.4%),薄基底膜肾病(TMN)3例(13%),Alport′s综合征(AS)、局灶性节段性硬化(FSGS)I、gM肾病(IgMN)各1例(各4.3%)。结论孤立性血尿患儿以MsPGN、MGA及IgAN为主,TMN、FSGS占一定比例,极少数患儿可出现严重肾小球硬化改变。
Objective To study the kidney histological categories of isolated hematuria in children. Methods Twenty - three children with isolated hernaturia were performed renal biopsy under real time ultrasound guidance utilizing menghini style negative pressure biopsy device after local anesthesia or general anesthesia. The renopuncture tissue was directly sent by the mail - hoxes to the remote pathologic service. All of the biopsies were examined by light microscopy, electron microscopy and immunohistochemistry. Results Biopsies were clarified as measangial proliferative glomerulonephritis（MsPGN） （8 cases）, minimal change nephropathy（MCN ）（5 cases）, IgA nephmpathy （ IgAN ） （4 cascs ）, thin basement membrane nephropathy（TMN ） （ 3 cases）, Alport＇s syndrome（ AS ） （ 1 case）, focal segmental glomerulosclerosis（FSGS） （ 1 case）and IgM nephropathy（IgMN） （ 1 case）. Conclusions In this series, MsPGN, MGA, IgAN are the most common biopsy diagnosis. TMN and Alport＇s are account for some proportion. A few IgMN and FSGS may also present as isolated hematuria.
出处
《实用儿科临床杂志》
CAS
CSCD
北大核心
2006年第17期1149-1150,共2页
Journal of Applied Clinical Pediatrics
关键词
血尿
肾小球肾炎
膜增生性
儿童
hematuria
glomerulonephritis, membranoprovi ferative
child
