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亚中毒阈剂量毒死蜱的神经发育毒性 被引量:1

Developmental neurotoxicity of chlorpyrifos at subthreshold dose of overt systemic toxicity
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作者 邓礼 赵玲玲
出处 《中国职业医学》 CAS 北大核心 2006年第5期390-392,共3页 China Occupational Medicine
基金 湖南省科技厅基金项目(02ssy3078)
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  • 1SLOTKIN T A, TATE C A, COUSINS M M, et al. Functional alterations in CNS catecholamine systems in adolescence and adulthood after neonatal chlorpyrifos exposure[J]. Brain Res Dev Brain Res, 2002,133(2) :163-173.
  • 2ROY T S, SEIDLER F J, SLOTKIN T A, et al. Morphologic effects of subtoxic neonatal chlorpyrifos exposure in developing rat brain: regionally selective alterations in neurons and gila[ J]. Brain Res Dev Brain Res, 2004, 148(2) : 197 -206.
  • 3ROY T S, SHARMA V, SEIDLER F J, et al. Quantitative morphological assessment reveals neuronal and glial deficits in hippocampus after a brief subtoxic exposure to chlorpyrifos in neonatal rats [ J ].Brain Res Dev Brain Res,2005,155( 1 ) : 71 -80.
  • 4RAINES K W, SEIDLER F J, SLOTKIN T A. Alterations in serotonin transporter expression in brain regions of rats exposed neonatally to chlorpyrifos [J]. Brain Res Dev Brain Res, 2001, 130(1): 65 -72.
  • 5GARCIA S J, SEIDLER F J, QIAO D, et al. Chlorpyrifos targets developing glia: effects on glia fibrillary acidic protein [ J ]. Brain Res Dev Brain Res, 2002, 133(2) : 151 - 161.
  • 6DAM K, SEIDLER F J, SLOTKIN T A, et al. Chlorpyrifos exposure during a critical neonatal period elicits gender-selective deficits in the development of coordination skills and locomotor activity [ J ]. Brain Res Dev Brain Res, 2000, 121(2) : 179 -187.
  • 7SLOTKIN T A, COUSINS M M, TATE C A, et al. Persistent cholinergic presynaptic deficits after neonatal chlorpyrifos exposure [ J ].Brain Res, 2001,902(2) : 229 -243.
  • 8QIAO D, SEIDLER F J, SLOTKIN T A. Developmental neurotoxicity of chlorpyrifos modeled in vitro: comparative effects of metabolites and other cholinesterase inhibitors on DNA synthesis in PC12 and C6 cells[J]. Environ Health Perspect, 2001, 109(9) : 909 -913.
  • 9GARCIA S J, SEIDLER F J, SLOTKIN T A. Developmental neurotoxicity elicited by prenatal or postnatal chlorpyrifos exposure: effects on neurospeciflc proteins indicate changing vulnerabilities[ J]. Environ Health Perspect, 2003, 111 ( 3 ) : 297 - 303.
  • 10MORLEY B J, HAPPE H K. Cholinerglc receptors:dual roles in transduction and plasticity[J]. Hear Res, 2000, 147(1 -2) : 104 -112.

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