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慢性布鲁氏菌病人血清抗体类型研究 被引量:2

A Study of the Antibody Types of Sera from Patients with Chronic Brucellosis
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摘要 采用ELISA间接法和MRPAH法检测慢性布鲁氏菌病人血清89份,发现不同病期的慢性病人均为IgG抗体滴度高,IgA和IgM抗体也可保持5年以上,但滴度很低。MRPAH结果表明IgA滴度随病程逐年升高,IgM滴度则逐年降低,IgA与IgM几何平均滴度比值随病程逐年增高、病程2年比值<1,超过2年则>1。 A total of 89 sample sera obtained from patients who suffered from chronic brucellosis were determined for the antibody types by means of ELISA and MRPAH. The results showed that IgG antibody titres were high in the patients at different stages of the chronic disease while both IgA and IgM antibody titres very low, but could persist in these cases for 5 years and over. However, the results obtained by MRPAH revealed that IgA antibody titres were elevated year by year with the course of the disease, and IgM lilres declined and that the ratio of the geomelric mean lilres of both IgA and IgM antibodies were elevaled year after year with the course of the disease, with the ralio < 1 in the patients who had suffered from thedisease for 2 years and the ratio > 1 in those for more than 2 years.
出处 《地方病通报》 1990年第4期41-44,共4页 Endemic Diseases Bulletin
关键词 血清检测 布鲁氏菌病 抗体类型 Brucellosis Antibody types ELISA MRPAH
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参考文献2

  • 1王伟导,牛新玲.混合反向抗球蛋白血凝试验及其测定抗布氏菌抗体的研究[J]中国地方病学杂志,1985(02).
  • 2余(氵贺)等.临床免疫技术[M]上海科学技术出版社,1982.

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