摘要
将46例地方性氟中毒病人分四个年龄组进行超声心动图检查,与氟病区和非氟病区各46名健康人进行对照观察。初步探讨了地方性氟中毒二维超声心动图的改变情况。结果表明:(1)氟病组主动脉壁增厚100％,厚度7.5～9.8mm,增厚呈周围性,其厚度与年龄、病程不相关;(2)氟病组主动脉壁中度以上增强37例(79.8%),对照Ⅰ组中度以上增强4例(8.7%);(3)M超主动脉根部搏动幅度,氟病组小于对照组;(4)氟病组31～40、41～50岁组左室后壁厚度大于对照组,房室腔及其它项目无差异。本组结果提示:地方性氟中毒可致主动脉硬化症,从而明显提早并加重大动脉的硬化为钙化过程,提出了氟性主动脉硬化症。并就其病理生理机制进行了讨论。
Forty-six patients with endemic fluorosis divided into 4 age groups were examined by 2DE with 92 (2 groups) normals from both endemic and normal areas as controls. Results were shown as follows: (1) All the patients' aortic walls were peripherally thickened to a range from 7.5 to 9.8mm, and not correlative with age and course; (2) In the fluoric group, the number of cases which had increased echoes more than medium on the aortic walls was 37(79.8%) while in control group I was 4(8.7%) and in control group Ⅱ was none; (3) The amplitude of aortic root's pulse observed by M-mode echo in the fluoric group was 5.91 ± 1.40mm, clearly smaller than the control groups (P<0.01); (4) The thickness of LVPW of fluorosis patients in the 2 age groups of 31-40 and 41-50 was much larger than those of the control groups (P< 0.01) while no difference was found in the thickness of other items among all the 3 groups. Results of this study suggest that endemic fluorosis might cause aortosclerosis, which greatly aggravate the course and range of sclerosis and calcification of the conducting arteries and which in turn make fluorosis severer. The term ' fluoric aortosclerosis' has been put forward and, its physiopathologic mechanism discussed.
出处
《地方病通报》
1990年第1期91-94,共4页
Endemic Diseases Bulletin
关键词
超声心动图
氟中毒
主动脉硬化
Echocardiography
Fluoric aortosclerosis
Edemic fluorosis
