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美百乐镇治疗不稳定型心绞痛疗效观察

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摘要 目的观察美百乐镇缓解不稳定型心绞痛(UAP)程度。方法46例UAP患者随机分为两组,两组患者在入院后常规治疗(如吸氧、速避凝、阿司匹林、硝酸脂类、倍他乐克、止痛、镇静、ACEI等),治疗组23例用美百乐镇20mg/d,睡前服,连服6个月,对照组仅常规治疗不给调脂治疗。观察两组患者于治疗后二周和治疗后四周心绞痛缓解程度、发作次数及半年左心室功能,治疗前后血脂情况。结果治疗二周两组间缓解心绞痛的显效率存在差异(88.6%、70.2%)(P<0.05),治疗组治疗前后血脂有明显差异(P<0.05),而对照组治疗前后无差异,两组半年左心室功能无统计学意义。结论美百乐镇联合应用常规抗心绞痛药物可以有效地缓解UAP。
作者 陈康
出处 《海南医学》 CAS 2006年第10期73-74,共2页 Hainan Medical Journal
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  • 1[1]Scandinavian Simvastatin Sur vival Study Group.Randomized trial of ch olesterol lowering in 4444 patients with coronary heart disease:the Scandinavan Simvastatin Survival Study(4S). Lancet,1994,344:1383-1389.
  • 2[2]The long-term Intervention with P ravastatin in Ischemic Disease(LIPID )Stud y Group.Prevention of cardiovascular eve nts and death with pravastatin in patien ts with coronary heart disease and a bro ad rang of initial cholesterol levels.N Engl J Med,1998,339:1349-1357.
  • 3[3]Forrester JS.Role of plaque ruptu re in acute coronary syndromes.Am J Card iol,2000,86(suppl.):155-235.
  • 4[4]Selwyn AP,Kinlay S,Libby P,et al .Atherogenic lipids,vascular dysfunction ,and clinical signs of ischemic heart di sease.Circulation,1997,95:5-7.
  • 5[5]Dupuis J,Tardif JC,Cernacek P,et al.Cholesterol reduction rapidly improve s endothelium function after acute coron ary syndrome:the RECIFE(Reduction of Cho lesterol in Ischemia and Function of the Endothelium)trial[see comm ents].[ BFQ〗Circulation,1999,99:3227-3233.
  • 6[6]ODriscoll G,Green D,Taylor RR.Simvast atin an HMG-coenzyme a reductase inhibit or,improves endothelial function within 1 month.Circulation,1997,95:1126-1131.
  • 7[7]Treasure CB,Klein JL,Weintraub WS ,et al.Beneficial effects of cholesterol -lowering therapy on the coronary endoth elium in patients with coronary artery d isease.N Engl Med,1995,332:481-487.
  • 8[8]Niwa S,Totsuka Y,Hayshi S.Inhibit ory effect of fluvastatin,an HMG-CoA red uctase inhibitor,on the expression of ad hesion molecules on human monocytes cell line.Int J Immunopharmacol,1996,18:669- 675.
  • 9[9]Bustos C,Hernandez-Presa MA,Ortego M,e t al.HMG-CoA reductase inhibition by ato rvastatin reduces neointimal inflammatio n in a rabbit model of atherosclerosis.J Am Coll Cardiol,1998,32:2057-2064.
  • 10[10]Albert MA,Danielson E,Rifai N,et al.Effect of statin therapy on creactiv e protein levels:the pravastatin inflamm ation/CRP evaluation(PRINCE):a randomizen trial and cohort study.JAMA,2 001,286:64-70.

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