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长春瑞滨联合顺铂同步放射治疗局部晚期非小细胞肺癌30例 被引量:1

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摘要 目的观察长春瑞滨联合顺铂同步放射治疗局部晚期非小细胞肺癌的近期疗效、毒副反应和耐受性。方法30例局部晚期非小细胞肺癌患者接受放化疗同步治疗。放射治疗采用60Co-γ射线,常规分割DT60 ̄70G/y6 ̄7周。放射治疗的第1,4周采用长春瑞滨(NVB)25m/gm2,第1,8天静脉推注,顺铂(DDP)30m/gm2第1 ̄3天静脉滴注。结果30例全部完成治疗,完全缓解(CR)率13.3%,部分缓解(PR)率70%,有效率(CR+PR)83.3%。白细胞下降发生率93.3%,Ⅲ、Ⅳ级占16.7%,放射性食管炎、放射性肺炎发生率分别为53.3%和13.3%,均为Ⅰ、Ⅱ级。治疗后Karnofsky评分提高≥10分者24例。结论长春瑞滨联合顺铂同步放射治疗局部晚期非小细胞肺癌有较好的近期疗效,毒副反应大多数患者均可耐受。
作者 张芳 郭培军
出处 《肿瘤研究与临床》 CAS 2006年第9期633-634,共2页 Cancer Research and Clinic
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