摘要
目的探讨急性高血压脑出血患者颅内血肿微创清除术后院内肺部感染的临床特征及防治原则.方法回顾性分析1999年1月～2005年3月急诊ICU、神经内科收治的急性高血压脑出血微创颅内血肿清除术患者,对其中33例院内肺部感染者与同期87例未发生院内肺部感染者进行对照,采集痰液标本进行细菌培养和药物敏感性试验.结果本组院内肺部感染率27.5%,病原体以G- 菌为主,常见的细菌为铜绿假单胞菌、大肠埃希菌、金黄色葡萄球菌.感染组GCS评分较对照组明显减低（P〈0.01）,而病死率（33.33%,11/33例）明显高于对照组（6.89%,6/87例）,P〈0.01.结论对急性高血压脑出血颅内血肿微创清除术患者,减少医源性感染的危险因素、监测病原体、合理选用抗生素、加强呼吸道痰液引流及营养支持等,均有利于院内肺部感染的防治.
Objective To explore the clinical characters and the principle of prevention and treatment of patients with acute hypertensive intracerebral hemorrhage. Methods We studies patients with micro-injury aspiration and drainage technique treatment of acute hypertensive intracerebral hemorrhage who were admitted at ICU of Emergency department and Neurological department from January 1999 to March 2005 by retrospective analysis. There were 33 patients with nosocomial pulmonary infection and 87 patients with non-nosocomial pulmonary infection among of them. We collected and cultured the samples of sputum and done antimicrobial susceptibility tests. Results The incidence of nosocomial pulmonary infection was 27. 5% in this group. The main pathogen was gram-negative bacillus,including Pseudomonas aeruginosa,Escbericbia coli and Staphylococcus aureus. Glasgow coma scale（GCS）score was significantly lower in group of nosocomial pulmonary infection than that in group of nonosocomial pulmonary infection（P〈0.01）. And the mortality was significantly higher in group of nosocomial pulmonary infection than that in group of no-nosocomial pulmonary infection （33. 33% VS 6. 89%,P〈0.01）. Conclusion For patients with micro-injury aspiration and drainage technique treatment of acute hypertensive intracerebral hemorrhage,reducing risk factor of nosocomial infection,inspecting pathogen,selecting reasonable antibiotics and augmenting suction and nutrition therapy can make for to prevent and treat nosocomial pulmonary infection.
出处
《中风与神经疾病杂志》
CAS
CSCD
北大核心
2006年第3期356-358,共3页
Journal of Apoplexy and Nervous Diseases
关键词
高血压
脑出血
交叉感染
肺部感染
微创术
抗生素
Hypertension
Intracerebral hemorrhage
Cross-infection
Pulmonary infection
Microinjury operation
Antibiotics
