摘要
检测３８４例健康老年吸烟者和１７６例健康老年非吸烟者血浆维生素Ｃ（Ｐ－ＶｉｔＣ）、维生素Ｅ（Ｐ－ＶｉｔＥ）、β－胡萝卜素（Ｐ－β－ＣＡＲ）、过氧化脂质（Ｐ－ＬＰＯ）含量和红细胞超氧化物歧化酶（Ｅ－ＳＯＤ）活性的结果表明，与非吸烟组比较，吸烟组的Ｐ－ＶｉｔＣ、Ｐ－ＶｉｔＥ、Ｐ－β－ＣＡＲ和Ｅ－ＳＯＤ平均值显著降低（Ｐ＜０．００１），而Ｐ－ＬＰＯ平均值显著升高（Ｐ＜０．００１）；８２例６１岁男性吸烟者Ｐ－ＶｉｔＣ、Ｐ－ＶｉｔＥ、Ｐ－β－ＣＡＲ和Ｅ－ＳＯＤ均随吸烟史及吸烟量的增加而降低，Ｐ－ＬＰＯ随吸烟史及吸烟量的增加而升高，并均呈一定程度的直线相关（Ｐ＜０．０００１）。提示老年吸烟者体内的氧化和抗氧化平衡严重失调，氧自由基反应和脂质过氧化反应明显加剧。
The results of measuring the plasma vitamin C(P VitC),vitamin E (P VitE),β carotene (P β CAR),lipoperoxides (P LPO)contents and erythrocyte superoxide dismutase (E SOD) activity of 384 healthy aged smokers and 176 healthy aged nonsmokers showed that the average P VitC,P VitE,P β CAR contents and E SOD activity of the smoker group were significantly lower than those of the nonsmoker group( P <0 001)and the average P LPO content of the smoker group was significantly higher than that of the healthy nonsmoker group ( P <0 001);82 smokers P VitC,P VitE,P β CAR and E SOD decreased as their smoking period and quantity increased ( P <0 001),and smokers P LPO content increased as their smoking period and quantity increased ( P <0 0001).It suggested that the balance between oxidation and antioxidation in the body of the smokers was apparently unbalanced and their oxygen free radical reaction and lipoperoxidation reaction significantly aggravated.
出处
《实用老年医学》
CAS
1996年第5期205-208,共4页
Practical Geriatrics
基金
浙江省卫生厅科研基金
关键词
吸烟
维生素C
过氧化脂质
超氧化物歧化酶
Smoking Vitamin C Vitamin E β Carotene Lipoperoxides Superoxide dismutase
